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Rab3c Gene Detail
Summary
  • Symbol
    Rab3c
  • Name
    RAB3C, member RAS oncogene family
  • Synonyms
    2700062I01Rik, 3110015B08Rik, 3110037E15Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914545
    NCBI Gene: 67295
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:110190721-110417530 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 61.19 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    7395 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914545
 protein coding gene Chr13:110190721-110417530 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020928
 protein coding gene Chr13:112440018-112679106 (-)
A/J MGP_AJ_G0020877
 protein coding gene Chr13:108007010-108232476 (-)
AKR/J MGP_AKRJ_G0020853
 protein coding gene Chr13:111263342-111494526 (-)
BALB/cJ MGP_BALBcJ_G0020878
 protein coding gene Chr13:108707503-108935034 (-)
C3H/HeJ MGP_C3HHeJ_G0020667
 protein coding gene Chr13:111043079-111268669 (-)
C57BL/6NJ MGP_C57BL6NJ_G0021313
 protein coding gene Chr13:115823297-116063851 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018882
 protein coding gene Chr13:103394509-103613707 (-)
CAST/EiJ MGP_CASTEiJ_G0020186
 protein coding gene Chr13:110611214-110857759 (-)
CBA/J MGP_CBAJ_G0020629
 protein coding gene Chr13:120260999-120507407 (-)
DBA/2J MGP_DBA2J_G0020752
 protein coding gene Chr13:107724689-107948914 (-)
FVB/NJ MGP_FVBNJ_G0020735
 protein coding gene Chr13:106399614-106629953 (-)
LP/J MGP_LPJ_G0020827
 protein coding gene Chr13:112526690-112757068 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020763
 protein coding gene Chr13:120667256-120912710 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0021351
 protein coding gene Chr13:110716185-110936420 (-)
PWK/PhJ MGP_PWKPhJ_G0019939
 protein coding gene Chr13:106441649-106663371 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019761
 protein coding gene Chr13:106975676-107210299 (-)
WSB/EiJ MGP_WSBEiJ_G0020244
 protein coding gene Chr13:111287824-111517150 (-)



Homology
more
  • Human Ortholog
    RAB3C, RAB3C, member RAS oncogene family
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RAB3C, RAB3C, member RAS oncogene family
  • Links
    NCBI Gene ID: 115827
    neXtProt AC: NX_Q96E17
    UniProt: Q96E17

  • Chr Location
    5q11.2; chr5:58582152-58859394 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 2 alleles in 2 genetic backgrounds
    14 phenotypes from multigenic genotypes
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele are viable and fertile.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    820
  • Tissues
    58
  • cDNA Data
    33
  • Literature Summary
    16
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 67295 NCBI Gene Model | MGI Sequence Detail 226810 C57BL/6J ±  kb
transcript NM_023852 RefSeq | MGI Sequence Detail 8500 C57BL/6  
polypeptide P62823 UniProt | EBI | MGI Sequence Detail 227 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 36
    cDNA 33
    Primer pair 2
    Other 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:1920367, MGI:1924255, MGI:2145303
References
more
  • Summaries
    All 62
    Developmental Gene Expression 16
    Gene Ontology 12
    Phenotypes 13
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory