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Lyzl1 Gene Detail
Summary
  • Symbol
    Lyzl1
  • Name
    lysozyme-like 1
  • Synonyms
    1700038F02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914578
    NCBI Gene: 67328
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:4165862-4182232 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 2.57 cM, cytoband A1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    426 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914578
 protein coding gene Chr18:4165832-4182232 (+)
129S1/SvImJ MGP_129S1SvImJ_G0024121
 protein coding gene Chr18:991077-1008080 (+)
A/J MGP_AJ_G0024083
 protein coding gene Chr18:1036295-1053217 (+)
AKR/J MGP_AKRJ_G0024051
 protein coding gene Chr18:1030489-1047520 (+)
BALB/cJ MGP_BALBcJ_G0024083
 protein coding gene Chr18:1033074-1049504 (+)
C3H/HeJ MGP_C3HHeJ_G0023848
 protein coding gene Chr18:1001781-1018288 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024528
 protein coding gene Chr18:1124568-1142507 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021967
 protein coding gene Chr18:878522-893577 (+)
CAST/EiJ MGP_CASTEiJ_G0023327
 protein coding gene Chr18:958497-975114 (+)
CBA/J MGP_CBAJ_G0023822
 protein coding gene Chr18:1089383-1110515 (+)
DBA/2J MGP_DBA2J_G0023950
 protein coding gene Chr18:973477-989964 (+)
FVB/NJ MGP_FVBNJ_G0023916
 protein coding gene Chr18:970278-985506 (+)
LP/J MGP_LPJ_G0024034
 protein coding gene Chr18:1077898-1096389 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023944
 protein coding gene Chr18:1114631-1132546 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024573
 protein coding gene Chr18:977775-993604 (+)
PWK/PhJ MGP_PWKPhJ_G0023072
 protein coding gene Chr18:985618-1002905 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022883
 protein coding gene Chr18:1246706-1262927 (+)
WSB/EiJ MGP_WSBEiJ_G0023393
 protein coding gene Chr18:1002869-1021594 (+)



Homology
more
  • Human Ortholog
    LYZL1, lysozyme like 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LYZL1, lysozyme like 1
  • Synonyms
    bA534G20.1, KAAG648, LYC2, LYZD1, PRO1278
  • Links
    NCBI Gene ID: 84569
    neXtProt AC: NX_Q6UWQ5
    UniProt: Q6UWQ5

  • Chr Location
    10p12.1-p11.23; chr10:29289061-29318328 (+)  GRCh38
  • Human Ortholog
    LYZL2, lysozyme like 2
  • Synonyms
    LYZD2
  • Links
    NCBI Gene ID: 119180
    neXtProt AC: NX_Q7Z4W2
    UniProt: Q7Z4W2

  • Chr Location
    10p11.23; chr10:30606221-30629762 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 3 alleles in 3 genetic backgrounds
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Female homozygous mutant mice exhibit a decreased mean heart rate. Male mice homozygous for a null allele display normal fertility and testis morphology.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    9
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67328 NCBI Gene Model | MGI Sequence Detail 16371 C57BL/6J ±  kb
    transcript NM_026092 RefSeq | MGI Sequence Detail 816 C57BL/6  
    polypeptide Q9CPX3 UniProt | EBI | MGI Sequence Detail 148 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 2
    References
    more
    • Summaries
      All 23
      Gene Ontology 3
      Phenotypes 5
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:263089 Khan M, et al., The evolutionarily conserved genes: Tex37, Ccdc73, Prss55 and Nxt2 are dispensable for fertility in mice. Sci Rep. 2018 Mar 21;8(1):4975
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory