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1700093K21Rik Gene Detail
Summary
  • Symbol
    1700093K21Rik
  • Name
    RIKEN cDNA 1700093K21 gene
  • Synonyms
    b2b3025Clo
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914608
    NCBI Gene: 67358
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:23466203-23471155 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 14.32 cM, cytoband A3.3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    227 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914608
 protein coding gene Chr11:23466203-23471915 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018088
 protein coding gene Chr11:21279140-21286032 (-)
A/J MGP_AJ_G0018061
 protein coding gene Chr11:20448190-20453146 (-)
AKR/J MGP_AKRJ_G0018025
 protein coding gene Chr11:21181253-21190209 (-)
BALB/cJ MGP_BALBcJ_G0018029
 protein coding gene Chr11:20589279-20594652 (-)
C3H/HeJ MGP_C3HHeJ_G0017843
 protein coding gene Chr11:21063812-21068717 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018481
 protein coding gene Chr11:22140409-22146732 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016139
 protein coding gene Chr11:19341385-19346235 (-)
CAST/EiJ MGP_CASTEiJ_G0017404
 protein coding gene Chr11:21089705-21094613 (-)
CBA/J MGP_CBAJ_G0017817
 protein coding gene Chr11:23122536-23127427 (-)
DBA/2J MGP_DBA2J_G0017927
 protein coding gene Chr11:20374334-20379569 (-)
FVB/NJ MGP_FVBNJ_G0017919
 protein coding gene Chr11:20153609-20158718 (-)
LP/J MGP_LPJ_G0017998
 protein coding gene Chr11:21376355-21383133 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017945
 protein coding gene Chr11:23649802-23654663 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018522
 protein coding gene Chr11:21292903-21299235 (-)
PWK/PhJ MGP_PWKPhJ_G0017185
 protein coding gene Chr11:20420989-20425955 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016982
 protein coding gene Chr11:21044175-21049757 (-)
WSB/EiJ MGP_WSBEiJ_G0017458
 protein coding gene Chr11:20928294-20934255 (-)



Homology
more
  • Human Ortholog
    C2orf74, chromosome 2 open reading frame 74
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    C2orf74, chromosome 2 open reading frame 74
  • Links
    NCBI Gene ID: 339804
    neXtProt AC: NX_A8MZ97
    UniProt: A8MZ97

  • Chr Location
    2p15; chr2:61145068-61164828 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with 1700093K21Rik mouse models

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 3 alleles in 3 genetic backgrounds
    9 images
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for an ENU-induced allele exhibit congenital heart defects associated with heterotaxy, as well as thoracic and abdominal visceral organ situs anomalies, and misaligned sternal vertebrae.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    17
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000020286 Ensembl Gene Model | MGI Sequence Detail 4953 C57BL/6J ±  kb
    transcript ENSMUST00000239488 Ensembl | MGI Sequence Detail 1002 Not Applicable  
    polypeptide ENSMUSP00000159376 Ensembl | MGI Sequence Detail 196 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 17
      cDNA 17

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:5618822
    References
    more
    • Summaries
      All 26
      Diseases 1
      Gene Ontology 1
      Phenotypes 9
    • Earliest
      J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory