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Entpd4 Gene Detail
Summary
  • Symbol
    Entpd4
  • Name
    ectonucleoside triphosphate diphosphohydrolase 4
  • Synonyms
    1200014F22Rik, A430102M06Rik, Lysal1, mKIAA0392
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914714
    NCBI Gene: 67464
  • Alliance
Location &
Maps
more
  • Sequence Map
    Chr14:69574600-69604191 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 14, 36.05 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    182 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914714
protein coding gene Chr14:69574600-69604719 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021521
protein coding gene Chr14:64122255-64140326 (+)
A/J MGP_AJ_G0021480
protein coding gene Chr14:62594722-62625020 (+)
AKR/J MGP_AKRJ_G0021456
protein coding gene Chr14:64688317-64717602 (+)
BALB/cJ MGP_BALBcJ_G0021486
protein coding gene Chr14:62569822-62599670 (+)
C3H/HeJ MGP_C3HHeJ_G0021263
protein coding gene Chr14:64415718-64444111 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021925
protein coding gene Chr14:67044332-67064069 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019465
protein coding gene Chr14:60434398-60463229 (+)
CAST/EiJ MGP_CASTEiJ_G0020780
protein coding gene Chr14:60964713-60984429 (+)
CBA/J MGP_CBAJ_G0021230
protein coding gene Chr14:69119393-69152660 (+)
DBA/2J MGP_DBA2J_G0021353
protein coding gene Chr14:62194327-62223842 (+)
FVB/NJ MGP_FVBNJ_G0021332
protein coding gene Chr14:61621448-61639429 (+)
LP/J MGP_LPJ_G0025867
protein coding gene Chr2:86335306-86364574 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021361
protein coding gene Chr14:68083068-68102310 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021948
protein coding gene Chr14:63962675-63980643 (+)
PWK/PhJ MGP_PWKPhJ_G0020524
protein coding gene Chr14:58953597-58971841 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020357
protein coding gene Chr14:59887112-59904997 (+)
WSB/EiJ MGP_WSBEiJ_G0020833
protein coding gene Chr14:64259973-64280320 (+)



Homology
more
  • Human Ortholog
    ENTPD4, ectonucleoside triphosphate diphosphohydrolase 4
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ENTPD4, ectonucleoside triphosphate diphosphohydrolase 4
  • Synonyms
    LALP70, LAP70, LYSAL1, NTPDase-4, UDPase
  • Links
    NCBI Gene ID: 9583
    neXtProt AC: NX_Q9Y227
    UniProt: Q9Y227

  • Chr Location
    8p21.3; chr8:23385783-23457695 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 67464 NCBI Gene Model | MGI Sequence Detail 29592 C57BL/6J ±  kb
transcript NM_026174 RefSeq | MGI Sequence Detail 3084 C57BL/6  
polypeptide Q9DBT4 UniProt | EBI | MGI Sequence Detail 613 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 19
    cDNA 17
    Primer pair 2

    Microarray probesets 3
Other
Accession IDs
less
MGI:1925183, MGI:2145630
References
more
  • Summaries
    All 36
    Developmental Gene Expression 6
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:307765 Boschen KE, et al., Transcriptomic analyses of gastrulation-stage mouse embryos with differential susceptibility to alcohol. Dis Model Mech. 2021 Jun 1;14(6):dmm049012

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory