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Akr1e1 Gene Detail
Summary
  • Symbol
    Akr1e1
  • Name
    aldo-keto reductase family 1, member E1
  • Synonyms
    1810061I10Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1914758
    NCBI Gene: 56043
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:4641122-4659163 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 2.57 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    628 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914758
 protein coding gene Chr13:4640749-4659173 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020210
 protein coding gene Chr13:1070312-1090446 (-)
A/J MGP_AJ_G0020166
 protein coding gene Chr13:1172013-1190505 (-)
AKR/J MGP_AKRJ_G0020141
 protein coding gene Chr13:1214986-1232708 (-)
BALB/cJ MGP_BALBcJ_G0020149
 protein coding gene Chr13:1183154-1204813 (-)
C3H/HeJ MGP_C3HHeJ_G0019953
 protein coding gene Chr13:1284782-1304362 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020596
 protein coding gene Chr13:1188551-1207817 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018206
 protein coding gene Chr13:1225616-1243364 (-)
CAST/EiJ MGP_CASTEiJ_G0019493
 protein coding gene Chr13:1106139-1123956 (-)
CBA/J MGP_CBAJ_G0019920
 protein coding gene Chr13:1181477-1199749 (-)
DBA/2J MGP_DBA2J_G0020037
 protein coding gene Chr13:1079888-1098462 (-)
FVB/NJ MGP_FVBNJ_G0020022
 protein coding gene Chr13:1036889-1058831 (-)
LP/J MGP_LPJ_G0020111
 protein coding gene Chr13:1186343-1204030 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020058
 protein coding gene Chr13:1300169-1326697 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020624
 protein coding gene Chr13:1161416-1179723 (-)
PWK/PhJ MGP_PWKPhJ_G0019254
 protein coding gene Chr13:1162535-1182010 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019061
 protein coding gene Chr13:1217766-1235271 (-)
WSB/EiJ MGP_WSBEiJ_G0019551
 protein coding gene Chr13:1100781-1118430 (-)



Homology
more
  • Human Ortholog
    AKR1E2, aldo-keto reductase family 1 member E2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AKR1E2, aldo-keto reductase family 1 member E2
  • Synonyms
    AKR1CL2, AKRDC1, htAKR, hTSP, HTSP1, LoopADR, TAKR
  • Links
    NCBI Gene ID: 83592
    neXtProt AC: NX_Q96JD6
    UniProt: Q96JD6

  • Chr Location
    10p15.1; chr10:4786629-4873237 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    810
  • Tissues
    100
  • cDNA Data
    41
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 56043 NCBI Gene Model | MGI Sequence Detail 18042 C57BL/6J ±  kb
transcript NM_018859 RefSeq | MGI Sequence Detail 1729 C57BL/6  
polypeptide Q9DCT1 UniProt | EBI | MGI Sequence Detail 301 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 43
    cDNA 43

    Microarray probesets 3
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 5
    Phenotypes 4
  • Earliest
    J:67252 Bohren KM, et al., Characterization of a novel murine aldo-keto reductase. Adv Exp Med Biol. 1997;414:455-64
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory