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Norad Gene Detail
Summary
  • Symbol
    Norad
  • Name
    non-coding RNA activated by DNA damage
  • Synonyms
    1810005K14Rik, 2900097C17Rik
  • Feature Type
    lncRNA gene
  • IDs
    MGI:1914767
    NCBI Gene: 347740
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:156229983-156234899 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 77.39 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    140 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1914767
 lncRNA gene Chr2:156229980-156234921 (-)
129S1/SvImJ MGP_129S1SvImJ_G0002065
 unclassified gene Chr6:120407883-120408221 (+)
A/J MGP_AJ_G0001009
 unclassified gene Chr2:36668164-36669234 (-)
AKR/J no annotation
BALB/cJ MGP_BALBcJ_G0001001
 unclassified gene Chr2:36717283-36718342 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0002160
 unclassified gene Chr6:123500764-123501105 (+)
CAROLI/EiJ no annotation
CAST/EiJ MGP_CASTEiJ_G0002328
 unclassified gene ChrX:143164115-143164452 (-)
CBA/J no annotation
DBA/2J no annotation
FVB/NJ no annotation
LP/J MGP_LPJ_G0000903
 unclassified gene Chr15:91135573-91135945 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ MGP_NZOHlLtJ_G0002504
 unclassified gene ChrX:163439279-163439622 (-)
PWK/PhJ MGP_PWKPhJ_G0002287
 unclassified gene ChrX:139934175-139934494 (-)
SPRET/EiJ MGP_SPRETEiJ_G0000922
 unclassified gene Chr2:158173970-158174308 (-)
WSB/EiJ MGP_WSBEiJ_G0002357
 unclassified gene ChrX:161309806-161310149 (-)



Homology
more
  • Human Ortholog
    NORAD, non-coding RNA activated by DNA damage
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NORAD, non-coding RNA activated by DNA damage
  • Synonyms
    LINC00657
  • Links
    NCBI Gene ID: 647979

  • Chr Location
    chr20:36045618-36051018 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice with a null allele exhibit a degenerative phenotype resembling premature aging, with kyphosis and intervertebral disk degeneration, and decreased cellularity of the nucleus pulposus.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    1
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    708
  • Tissues
    2
  • cDNA Data
    193
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    • All Sequences
      25
    • RefSeq
      1
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 347740 NCBI Gene Model | MGI Sequence Detail 4917 C57BL/6J ±  kb
    transcript NR_024329 RefSeq | MGI Sequence Detail 4930 Not Specified  
    For the selected sequence
    Molecular
    Reagents
    less
    • All nucleic 193
      cDNA 193

      Microarray probesets 1
    Other
    Accession IDs
    less
    MGI:1916273, MGI:6392021
    References
    more
    • Summaries
      All 21
      Developmental Gene Expression 2
      Gene Ontology 1
      Phenotypes 4
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:340253 Zhang J, et al., LncRNA NORAD defects deteriorate the formation of age-related macular degeneration. Aging (Albany NY). 2023 Jul 29;15(15):7513-7532
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory