Lipf MGI Mouse Gene Detail - MGI:1914967

Symbol

Lipf
Name

lipase, gastric
Synonyms

2310051B21Rik

Feature Type

protein coding gene
IDs

MGI:1914967
NCBI Gene: 67717
Alliance

gene page
Transcription Start Sites

15 TSS

Sequence Map

Chr19:33938648-33954213 bp, + strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 19, 29.29 cM
Mapping Data

2 experiments

SNPs within 2kb

559 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1914967	protein coding gene	Chr19:33938587-33954213 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0025049	protein coding gene	Chr19:32690926-32706644 (+)
A/J	MGP_AJ_G0025027	protein coding gene	Chr19:31099958-31115567 (+)
AKR/J	MGP_AKRJ_G0024993	protein coding gene	Chr19:32150159-32165754 (+)
BALB/cJ	MGP_BALBcJ_G0025023	protein coding gene	Chr19:31213378-31228942 (+)
C3H/HeJ	MGP_C3HHeJ_G0024782	protein coding gene	Chr19:32247261-32262886 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0025464	protein coding gene	Chr19:33625437-33641189 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0022882	protein coding gene	Chr19:30550805-30568304 (+)
CAST/EiJ	MGP_CASTEiJ_G0024252	protein coding gene	Chr19:31978959-31999246 (+)
CBA/J	MGP_CBAJ_G0024759	protein coding gene	Chr19:35203070-35224506 (+)
DBA/2J	MGP_DBA2J_G0024891	protein coding gene	Chr19:31005269-31021077 (+)
FVB/NJ	MGP_FVBNJ_G0024852	protein coding gene	Chr19:30843861-30859492 (+)
LP/J	MGP_LPJ_G0024977	protein coding gene	Chr19:32778195-32793796 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0024883	protein coding gene	Chr19:35023630-35043692 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0025522	protein coding gene	Chr19:32245827-32261398 (+)
PWK/PhJ	MGP_PWKPhJ_G0024001	protein coding gene	Chr19:30814208-30830135 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0023802	protein coding gene	Chr19:31108862-31124834 (+)
WSB/EiJ	MGP_WSBEiJ_G0024316	protein coding gene	Chr19:32333301-32348859 (+)

Human Ortholog

LIPF, lipase F, gastric type

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

LIPF, lipase F, gastric type
Synonyms

GL, HGL, HLAL
Links

HGNC:6622

NCBI Gene ID: 8513

neXtProt AC: NX_P07098

UniProt: P07098
Chr Location

10q23.31; chr10:88664441-88678814 (+) GRCh38

MGI Vertebrate Homology

Lipf stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: LIPF
Protein SuperFamily

Steryl_ester_lip
Gene Tree

Lipf

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Phenotype Summary

4 phenotype references

All Mutations and Alleles

6
Endonuclease-mediated

3
Targeted

3
Incidental Mutations

CvDC
Find Mice (IMSR)

28 strains or lines available

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All GO Annotations

10
GO References

7

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

709
Tissues

1
cDNA Data

56
Literature Summary

1

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

ZFIN lipf

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All Sequences

76
RefSeq

4
UniProt

1
CCDS

CCDS29754.1

Ensembl

ENSMUSG00000024768 (Evidence)
NCBI Gene

67717

			Length	Strain/Species	Flank
genomic	67717	NCBI Gene Model \| MGI Sequence Detail	15566	C57BL/6J	± kb
transcript	NM_026334	RefSeq \| MGI Sequence Detail	1353	C57BL/6
polypeptide	Q9CPP7	UniProt \| EBI \| MGI Sequence Detail	395	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000009835 gastric triacylglycerol lipase

(term hierarchy)
EC

3.1.1.3
InterPro Domains

IPR029058 Alpha/Beta hydrolase fold

IPR025483 Lipase, eukaryotic

IPR006693 Partial AB-hydrolase lipase domain
GlyGen

Q9CPP7 2 sites

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All nucleic 57

cDNA 56

Primer pair 1

Microarray probesets 3

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MGI:2147672

Summaries

All 30

Developmental Gene Expression 1

Gene Ontology 7

Phenotypes 4
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

TSS for Lipf:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr156013	Chr19:33938549-33938554 (+)	-96 bp
Tssr156014	Chr19:33938557-33938562 (+)	-88 bp
Tssr156015	Chr19:33938584-33938587 (+)	-62 bp
Tssr156016	Chr19:33938595-33938610 (+)	-45 bp
Tssr156017	Chr19:33938614-33938655 (+)	-13 bp
Tssr156018	Chr19:33941940-33941952 (+)	3,298 bp
Tssr156019	Chr19:33942245-33942255 (+)	3,602 bp
Tssr5488	Chr19:33943049-33943050 (+)	4,402 bp
Tssr156020	Chr19:33946163-33946174 (+)	7,521 bp
Tssr156021	Chr19:33948156-33948161 (+)	9,511 bp
Tssr156022	Chr19:33948170-33948178 (+)	9,526 bp
Tssr156023	Chr19:33948218-33948230 (+)	9,576 bp
Tssr156024	Chr19:33950420-33950466 (+)	11,795 bp
Tssr156025	Chr19:33953869-33953878 (+)	15,226 bp
Tssr156026	Chr19:33954118-33954132 (+)	15,477 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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