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Caap1 Gene Detail
Summary
  • Symbol
    Caap1
  • Name
    caspase activity and apoptosis inhibitor 1
  • Synonyms
    5830433M19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915020
    NCBI Gene: 67770
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:94388318-94445033 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 43.32 cM, cytoband C5
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1160 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915020
 protein coding gene Chr4:94388318-94445033 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028448
 protein coding gene Chr4:94556734-94616208 (-)
A/J MGP_AJ_G0028411
 protein coding gene Chr4:91243277-91301144 (-)
AKR/J MGP_AKRJ_G0028358
 protein coding gene Chr4:93407356-93467027 (-)
BALB/cJ MGP_BALBcJ_G0028429
 protein coding gene Chr4:91492268-91549111 (-)
C3H/HeJ MGP_C3HHeJ_G0028142
 protein coding gene Chr4:94247488-94308539 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028868
 protein coding gene Chr4:98161564-98221564 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026162
 protein coding gene Chr4:86774521-86830870 (-)
CAST/EiJ MGP_CASTEiJ_G0027582
 protein coding gene Chr4:92116189-92175425 (-)
CBA/J MGP_CBAJ_G0028111
 protein coding gene Chr4:101152242-101219914 (-)
DBA/2J MGP_DBA2J_G0028261
 protein coding gene Chr4:91023440-91081028 (-)
FVB/NJ MGP_FVBNJ_G0028228
 protein coding gene Chr4:89883439-89945518 (-)
LP/J MGP_LPJ_G0028361
 protein coding gene Chr4:94876506-94936619 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028257
 protein coding gene Chr4:106909718-106983523 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028906
 protein coding gene Chr4:93697114-93755276 (-)
PWK/PhJ MGP_PWKPhJ_G0027307
 protein coding gene Chr4:89181632-89239083 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027127
 protein coding gene Chr4:91116397-91172649 (-)
WSB/EiJ MGP_WSBEiJ_G0027660
 protein coding gene Chr4:93860087-93917994 (-)



Homology
more
  • Human Ortholog
    CAAP1, caspase activity and apoptosis inhibitor 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CAAP1, caspase activity and apoptosis inhibitor 1
  • Synonyms
    C9orf82, CAAP
  • Links
    NCBI Gene ID: 79886
    neXtProt AC: NX_Q9H8G2
    UniProt: Q9H8G2

  • Chr Location
    9p21.2; chr9:26840685-26892803 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    8 phenotype references
  • All Mutations and Alleles
    11
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    1
  • Gene trapped
    7
  • Radiation induced
    1
  • Genomic Mutations
    3 involving Caap1
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    15 strains or lines available
Mice homozygous for a null allele exhibit no abnormalities.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    4
  • GO References
    4
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    13
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 67770 NCBI Gene Model | MGI Sequence Detail 56716 C57BL/6J ±  kb
transcript NM_026368 RefSeq | MGI Sequence Detail 2107 C57BL/6  
polypeptide Q8VDY9 UniProt | EBI | MGI Sequence Detail 356 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 4
Other
Accession IDs
less
MGI:2140329
References
more
  • Summaries
    All 35
    Gene Ontology 4
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:273282 Aslam MA, et al., Towards an understanding of C9orf82 protein/CAAP1 function. PLoS One. 2019;14(1):e0210526
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory