About   Help   FAQ
Brix1 Gene Detail
Summary
  • Symbol
    Brix1
  • Name
    BRX1, biogenesis of ribosomes
  • Synonyms
    1110064N10Rik, Bxdc2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915082
    NCBI Gene: 67832
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:10474865-10486023 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 5.35 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    471 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915082
 protein coding gene Chr15:10474865-10486033 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021722
 protein coding gene Chr15:7613624-7624730 (-)
A/J MGP_AJ_G0021682
 protein coding gene Chr15:7407368-7418917 (-)
AKR/J MGP_AKRJ_G0021660
 protein coding gene Chr15:7582937-7594145 (-)
BALB/cJ MGP_BALBcJ_G0021689
 protein coding gene Chr15:7324708-7336214 (-)
C3H/HeJ MGP_C3HHeJ_G0021465
 protein coding gene Chr15:7528888-7540400 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022128
 protein coding gene Chr15:7896706-7909087 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019665
 protein coding gene Chr15:6882403-6893433 (-)
CAST/EiJ MGP_CASTEiJ_G0020981
 protein coding gene Chr15:7584865-7595831 (-)
CBA/J MGP_CBAJ_G0021434
 protein coding gene Chr15:8076711-8093428 (-)
DBA/2J MGP_DBA2J_G0021558
 protein coding gene Chr15:7277939-7289645 (-)
FVB/NJ MGP_FVBNJ_G0021536
 protein coding gene Chr15:7138968-7149938 (-)
LP/J MGP_LPJ_G0021626
 protein coding gene Chr15:7511539-7522733 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021561
 protein coding gene Chr15:8364852-8376618 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022151
 protein coding gene Chr15:7547138-7563161 (-)
PWK/PhJ MGP_PWKPhJ_G0020724
 protein coding gene Chr15:7441812-7453266 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020562
 protein coding gene Chr15:7506749-7517296 (-)
WSB/EiJ MGP_WSBEiJ_G0021037
 protein coding gene Chr15:7557067-7568067 (-)



Homology
more
  • Human Ortholog
    BRIX1, biogenesis of ribosomes BRX1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    BRIX1, biogenesis of ribosomes BRX1
  • Synonyms
    BRIX, BXDC2
  • Links
    NCBI Gene ID: 55299
    neXtProt AC: NX_Q8TDN6
    UniProt: Q8TDN6

  • Chr Location
    5p13.2; chr5:34915677-34925996 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    85
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67832 NCBI Gene Model | MGI Sequence Detail 11159 C57BL/6J ±  kb
transcript NM_026396 RefSeq | MGI Sequence Detail 2654 C57BL/6  
polypeptide Q9DCA5 UniProt | EBI | MGI Sequence Detail 353 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 85
    cDNA 85

    Microarray probesets 5
Other
Accession IDs
less
MGI:2146272
References
more
  • Summaries
    All 35
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory