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Echdc3 Gene Detail
Summary
  • Symbol
    Echdc3
  • Name
    enoyl Coenzyme A hydratase domain containing 3
  • Synonyms
    2310005D12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915106
    NCBI Gene: 67856
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:6193276-6217805 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 3.62 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    911 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915106
 protein coding gene Chr2:6193276-6217844 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025330
 protein coding gene Chr2:3341208-3363087 (-)
A/J MGP_AJ_G0025307
 protein coding gene Chr2:3179840-3201742 (-)
AKR/J MGP_AKRJ_G0025275
 protein coding gene Chr2:3281345-3304343 (-)
BALB/cJ MGP_BALBcJ_G0025303
 protein coding gene Chr2:3167739-3191422 (-)
C3H/HeJ MGP_C3HHeJ_G0025063
 protein coding gene Chr2:3218229-3243286 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025745
 protein coding gene Chr2:3444303-3468409 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023159
 protein coding gene Chr2:2983017-3003897 (-)
CAST/EiJ MGP_CASTEiJ_G0024526
 protein coding gene Chr2:3288872-3310655 (-)
CBA/J MGP_CBAJ_G0025042
 protein coding gene Chr2:3596058-3617902 (-)
DBA/2J MGP_DBA2J_G0025174
 protein coding gene Chr2:3122502-3146132 (-)
FVB/NJ MGP_FVBNJ_G0025136
 protein coding gene Chr2:3126371-3154401 (-)
LP/J MGP_LPJ_G0025260
 protein coding gene Chr2:3288048-3309919 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025168
 protein coding gene Chr2:3410066-3433394 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025803
 protein coding gene Chr2:3278080-3301527 (-)
PWK/PhJ MGP_PWKPhJ_G0024277
 protein coding gene Chr2:3123186-3142988 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024077
 protein coding gene Chr2:3248639-3274460 (-)
WSB/EiJ MGP_WSBEiJ_G0024596
 protein coding gene Chr2:3319883-3343712 (-)



Homology
more
  • Human Ortholog
    ECHDC3, enoyl-CoA hydratase domain containing 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ECHDC3, enoyl-CoA hydratase domain containing 3
  • Links
    NCBI Gene ID: 79746
    neXtProt AC: NX_Q96DC8
    UniProt: Q96DC8

  • Chr Location
    10p14; chr10:11742366-11764070 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    10
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    42
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67856 NCBI Gene Model | MGI Sequence Detail 24530 C57BL/6J ±  kb
transcript NM_024208 RefSeq | MGI Sequence Detail 1812 C57BL/6  
polypeptide Q9D7J9 UniProt | EBI | MGI Sequence Detail 300 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000031572 enoyl-CoA hydratase domain-containing protein 3, mitochondrial
    (term hierarchy)
  • InterPro Domains
    IPR029045 ClpP/crotonase-like domain superfamily
    IPR014748 Enoyl-CoA hydratase, C-terminal
    IPR001753 Enoyl-CoA hydratase/isomerase
    IPR052377 Mitochondrial enoyl-CoA hydratase domain-containing protein
  • GlyGen
    Q9D7J9 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 42
    cDNA 42

    Microarray probesets 4
Other
Accession IDs
less
MGI:2139036
References
more
  • Summaries
    All 31
    Gene Ontology 7
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory