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Tmem33 Gene Detail
Summary
  • Symbol
    Tmem33
  • Name
    transmembrane protein 33
  • Synonyms
    1110006G02Rik, 1600019D15Rik, 2410089A21Rik, 2700052H22Rik, 5430406L04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915128
    NCBI Gene: 67878
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:67417908-67448804 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 36.00 cM, cytoband D
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    779 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915128
 protein coding gene Chr5:67417908-67448804 (+)
129S1/SvImJ MGP_129S1SvImJ_G0029593
 protein coding gene Chr5:67038829-67063402 (+)
A/J MGP_AJ_G0029561
 protein coding gene Chr5:64525236-64549830 (+)
AKR/J MGP_AKRJ_G0029509
 protein coding gene Chr5:66592440-66618515 (+)
BALB/cJ MGP_BALBcJ_G0029570
 protein coding gene Chr5:65210026-65234775 (+)
C3H/HeJ MGP_C3HHeJ_G0029293
 protein coding gene Chr5:66911403-66936530 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030024
 protein coding gene Chr5:69809519-69842003 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027264
 protein coding gene Chr5:60578839-60601837 (+)
CAST/EiJ MGP_CASTEiJ_G0028701
 protein coding gene Chr5:66087030-66118802 (+)
CBA/J MGP_CBAJ_G0029262
 protein coding gene Chr5:72052921-72078153 (+)
DBA/2J MGP_DBA2J_G0029408
 protein coding gene Chr5:64545401-64569730 (+)
FVB/NJ MGP_FVBNJ_G0029368
 protein coding gene Chr5:63719358-63743603 (+)
LP/J MGP_LPJ_G0029493
 protein coding gene Chr5:67530226-67555417 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029396
 protein coding gene Chr5:74841112-74869702 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030057
 protein coding gene Chr5:66261483-66287327 (+)
PWK/PhJ MGP_PWKPhJ_G0028425
 protein coding gene Chr5:63582005-63607759 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028259
 protein coding gene Chr5:65598992-65622150 (+)
WSB/EiJ MGP_WSBEiJ_G0028781
 protein coding gene Chr5:66498768-66524357 (+)



Homology
more
  • Human Ortholog
    TMEM33, transmembrane protein 33
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM33, transmembrane protein 33
  • Synonyms
    1600019D15Rik, Pom33, SHINC-3, SHINC3
  • Links
    NCBI Gene ID: 55161
    neXtProt AC: NX_P57088
    UniProt: P57088

  • Chr Location
    4p13; chr4:41935129-41960803 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    28 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    798
  • Tissues
    36
  • cDNA Data
    25
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 67878 NCBI Gene Model | MGI Sequence Detail 30897 C57BL/6J ±  kb
    transcript NM_001285452 RefSeq | MGI Sequence Detail 6404 C57BL/6  
    polypeptide Q9CR67 UniProt | EBI | MGI Sequence Detail 247 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 25
      cDNA 25

      Microarray probesets 12
    Other
    Accession IDs
    less
    MGI:1915829, MGI:1921744, MGI:1924069, MGI:1925743, MGI:2140828, MGI:2140867, MGI:3035502
    References
    more
    • Summaries
      All 57
      Developmental Gene Expression 2
      Gene Ontology 6
      Phenotypes 28
    • Earliest
      J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/17/2024
    MGI 6.24     		The Jackson Laboratory