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Ppm1m Gene Detail
Summary
  • Symbol
    Ppm1m
  • Name
    protein phosphatase 1M
  • Synonyms
    2810423O19Rik, PP2C eta
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915155
    NCBI Gene: 67905
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:106072152-106076432 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 57.46 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    207 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915155
 protein coding gene Chr9:106072146-106076945 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035222
 protein coding gene Chr9:107976053-107981691 (-)
A/J MGP_AJ_G0035202
 protein coding gene Chr9:104089315-104094901 (-)
AKR/J MGP_AKRJ_G0035134
 protein coding gene Chr9:106679426-106685029 (-)
BALB/cJ MGP_BALBcJ_G0035195
 protein coding gene Chr9:103771352-103777019 (-)
C3H/HeJ MGP_C3HHeJ_G0034905
 protein coding gene Chr9:107086907-107092526 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035715
 protein coding gene Chr9:110937954-110943492 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032613
 protein coding gene Chr9:101583550-101589297 (-)
CAST/EiJ MGP_CASTEiJ_G0034217
 protein coding gene Chr9:106977061-106982621 (-)
CBA/J MGP_CBAJ_G0034874
 protein coding gene Chr9:114840838-114846472 (-)
DBA/2J MGP_DBA2J_G0035035
 protein coding gene Chr9:103547484-103553078 (-)
FVB/NJ MGP_FVBNJ_G0034983
 protein coding gene Chr9:102320029-102325620 (-)
LP/J MGP_LPJ_G0035111
 protein coding gene Chr9:108200945-108206565 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035022
 protein coding gene Chr9:116495515-116503071 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035737
 protein coding gene Chr9:106918345-106923938 (-)
PWK/PhJ MGP_PWKPhJ_G0033924
 protein coding gene Chr9:103841319-103846973 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033759
 protein coding gene Chr9:106976878-106982570 (-)
WSB/EiJ MGP_WSBEiJ_G0034337
 protein coding gene Chr9:106818736-106824402 (-)



Homology
more
  • Human Ortholog
    PPM1M, protein phosphatase, Mg2+/Mn2+ dependent 1M
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PPM1M, protein phosphatase, Mg2+/Mn2+ dependent 1M
  • Synonyms
    PP2CE, PP2C-eta, PP2Ceta
  • Links
    NCBI Gene ID: 132160
    neXtProt AC: NX_Q96MI6
    UniProt: Q96MI6

  • Chr Location
    3p21.2; chr3:52245759-52250599 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    715
  • Tissues
    8
  • cDNA Data
    34
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 67905 NCBI Gene Model | MGI Sequence Detail 4281 C57BL/6J ±  kb
transcript NM_198931 RefSeq | MGI Sequence Detail 1848 Not Specified  
polypeptide Q8BU27 UniProt | EBI | MGI Sequence Detail 462 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 35
    cDNA 35

    Microarray probesets 3
Other
Accession IDs
less
MGI:2143341, MGI:2143383
References
more
  • Summaries
    All 36
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 10
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory