About   Help   FAQ
Mpnd Gene Detail
Summary
  • Symbol
    Mpnd
  • Name
    MPN domain containing
  • Synonyms
    E130307M08Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915297
    NCBI Gene: 68047
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:56316201-56323790 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 29.11 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    229 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915297
 protein coding gene Chr17:56312711-56323790 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023907
 protein coding gene Chr17:57626781-57641849 (+)
A/J MGP_AJ_G0023867
 protein coding gene Chr17:56076737-56088466 (+)
AKR/J MGP_AKRJ_G0023836
 protein coding gene Chr17:56761701-56774250 (+)
BALB/cJ MGP_BALBcJ_G0023868
 protein coding gene Chr17:55912082-55923578 (+)
C3H/HeJ MGP_C3HHeJ_G0023631
 protein coding gene Chr17:57469565-57481821 (+)
C57BL/6NJ MGP_C57BL6NJ_G0024312
 protein coding gene Chr17:59910842-59925987 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021759
 protein coding gene Chr17:52595037-52606339 (+)
CAST/EiJ MGP_CASTEiJ_G0023114
 protein coding gene Chr17:57772297-57786186 (+)
CBA/J MGP_CBAJ_G0023608
 protein coding gene Chr17:62213750-62231568 (+)
DBA/2J MGP_DBA2J_G0023736
 protein coding gene Chr17:54811118-54823196 (+)
FVB/NJ MGP_FVBNJ_G0023702
 protein coding gene Chr17:54326745-54340335 (+)
LP/J MGP_LPJ_G0023816
 protein coding gene Chr17:58352521-58364590 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023729
 protein coding gene Chr17:61778376-61791779 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0024357
 protein coding gene Chr17:57137695-57148555 (+)
PWK/PhJ MGP_PWKPhJ_G0022859
 protein coding gene Chr17:54154618-54165440 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022671
 protein coding gene Chr17:53900042-53914796 (+)
WSB/EiJ MGP_WSBEiJ_G0023178
 protein coding gene Chr17:57749857-57762094 (+)



Homology
more
  • Human Ortholog
    MPND, MPN domain containing
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MPND, MPN domain containing
  • Links
    NCBI Gene ID: 84954
    neXtProt AC: NX_Q8N594
    UniProt: Q8N594

  • Chr Location
    19p13.3; chr19:4343527-4360086 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    741
  • Tissues
    28
  • cDNA Data
    8
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68047 NCBI Gene Model | MGI Sequence Detail 7590 C57BL/6J ±  kb
    transcript NM_026530 RefSeq | MGI Sequence Detail 1701 C57BL/6  
    polypeptide Q3TV65 UniProt | EBI | MGI Sequence Detail 487 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 9
      cDNA 9

      Microarray probesets 2
    References
    more
    • Summaries
      All 28
      Developmental Gene Expression 4
      Gene Ontology 2
      Phenotypes 7
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:226028 Lewandowski JP, et al., Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol. 2015 Oct 1;406(1):92-103
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory