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Akirin1 Gene Detail
Summary
  • Symbol
    Akirin1
  • Name
    akirin 1
  • Synonyms
    6330407G11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915300
    NCBI Gene: 68050
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:123628988-123644092 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 57.42 cM, cytoband D1
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    402 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915300
 protein coding gene Chr4:123628352-123644138 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028743
 protein coding gene Chr4:125210694-125229333 (-)
A/J MGP_AJ_G0028702
 protein coding gene Chr4:120319777-120336541 (-)
AKR/J MGP_AKRJ_G0028655
 protein coding gene Chr4:123596249-123616219 (-)
BALB/cJ MGP_BALBcJ_G0028725
 protein coding gene Chr4:120888033-120903288 (-)
C3H/HeJ MGP_C3HHeJ_G0028440
 protein coding gene Chr4:123685464-123706249 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029166
 protein coding gene Chr4:130035745-130052532 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026439
 protein coding gene Chr4:113515613-113531959 (-)
CAST/EiJ MGP_CASTEiJ_G0027872
 protein coding gene Chr4:121718833-121735676 (-)
CBA/J MGP_CBAJ_G0028405
 protein coding gene Chr4:133321698-133337943 (-)
DBA/2J MGP_DBA2J_G0028554
 protein coding gene Chr4:120805931-120823209 (-)
FVB/NJ MGP_FVBNJ_G0028521
 protein coding gene Chr4:119430638-119445433 (-)
LP/J MGP_LPJ_G0028655
 protein coding gene Chr4:125499391-125513290 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028547
 protein coding gene Chr4:138269908-138286104 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029204
 protein coding gene Chr4:123967455-123984937 (-)
PWK/PhJ MGP_PWKPhJ_G0027592
 protein coding gene Chr4:117202202-117217008 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027419
 protein coding gene Chr4:119753118-119771533 (-)
WSB/EiJ MGP_WSBEiJ_G0027951
 protein coding gene Chr4:124027140-124043669 (-)



Homology
more
  • Human Ortholog
    AKIRIN1, akirin 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    AKIRIN1, akirin 1
  • Synonyms
    C1orf108, STRF2
  • Links
    NCBI Gene ID: 79647
    neXtProt AC: NX_Q9H9L7
    UniProt: Q9H9L7

  • Chr Location
    1p34.3; chr1:38991276-39006059 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    2
  • Gene trapped
    3
  • Radiation induced
    1
  • Targeted
    3
  • Genomic Mutations
    4 involving Akirin1
  • Incidental Mutations
    CvDC
  • Find Mice (IMSR)
    15 strains or lines available
Mice homozygous for a knock-out allele are viable, healthy and do not exhibit any gross developmental abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    23
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    858
  • Tissues
    28
  • cDNA Data
    14
  • Literature Summary
    4
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 68050 NCBI Gene Model | MGI Sequence Detail 15105 C57BL/6J ±  kb
transcript NM_023423 RefSeq | MGI Sequence Detail 2383 C57BL/6  
polypeptide Q99LF1 UniProt | EBI | MGI Sequence Detail 191 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 15
    Primer pair 1
    Other 1

    Microarray probesets 5
References
more
  • Summaries
    All 39
    Developmental Gene Expression 4
    Gene Ontology 8
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:302825 Rao VV, et al., Role of Akirin1 in the regulation of skeletal muscle fiber-type switch. J Cell Biochem. 2019 Feb 11;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory