Ociad1 MGI Mouse Gene Detail - MGI:1915345

Symbol

Ociad1
Name

OCIA domain containing 1
Synonyms

6030432N09Rik, Asrij, B230209J16Rik, Emi2, expressed during mesenchymal induction 2, Imi2, TPA018

Feature Type

protein coding gene
IDs

MGI:1915345
NCBI Gene: 68095
Alliance

gene page
Transcription Start Sites

6 TSS

Sequence Map

Chr5:73450127-73471412 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 5, 38.44 cM
Mapping Data

2 experiments

SNPs within 2kb

512 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1915345	protein coding gene	Chr5:73450093-73471420 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0029623	protein coding gene	Chr5:73286234-73307296 (+)
A/J	MGP_AJ_G0029591	protein coding gene	Chr5:70543238-70564293 (+)
AKR/J	MGP_AKRJ_G0029539	protein coding gene	Chr5:72825932-72846985 (+)
BALB/cJ	MGP_BALBcJ_G0029600	protein coding gene	Chr5:71260751-71281813 (+)
C3H/HeJ	MGP_C3HHeJ_G0029323	protein coding gene	Chr5:73229253-73250297 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0030054	protein coding gene	Chr5:76299601-76321899 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0027294	protein coding gene	Chr5:66240360-66262086 (+)
CAST/EiJ	MGP_CASTEiJ_G0028731	protein coding gene	Chr5:72294607-72317566 (+)
CBA/J	MGP_CBAJ_G0029292	protein coding gene	Chr5:78784563-78805607 (+)
DBA/2J	MGP_DBA2J_G0029437	protein coding gene	Chr5:70622698-70643742 (+)
FVB/NJ	MGP_FVBNJ_G0029398	protein coding gene	Chr5:69758518-69779949 (+)
LP/J	MGP_LPJ_G0029523	protein coding gene	Chr5:73723348-73744403 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0029425	protein coding gene	Chr5:82080412-82102552 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0030087	protein coding gene	Chr5:72372438-72393498 (+)
PWK/PhJ	MGP_PWKPhJ_G0028454	protein coding gene	Chr5:69589115-69610848 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0028289	protein coding gene	Chr5:71722821-71743629 (+)
WSB/EiJ	MGP_WSBEiJ_G0028811	protein coding gene	Chr5:72663776-72684810 (+)

Human Ortholog

OCIAD1, OCIA domain containing 1

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

OCIAD1, OCIA domain containing 1
Synonyms

ASRIJ, OCIA, TPA018
Links

HGNC:16074

NCBI Gene ID: 54940

neXtProt AC: NX_Q9NX40

UniProt: Q9NX40
Chr Location

4p11; chr4:48805156-48861817 (+) GRCh38

MGI Vertebrate Homology

Ociad1 stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: OCIAD1
Gene Tree

Ociad1

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References

1 with disease annotations

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Phenotype Summary

33 phenotypes from 3 alleles in 3 genetic backgrounds
367 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

43
Chemically induced (other)

2
Endonuclease-mediated

1
Gene trapped

33
Radiation induced

1
Spontaneous

3
Targeted

3
Genomic Mutations

6 involving Ociad1
Incidental Mutations

Mutagenetix , APF , CvDC
Find Mice (IMSR)

31 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

Mice homozygous for a null allele display increased hematopoitic cell numbers and proliferation, progressive increase in peripheral blood cells, decreased lifespans, splenomegaly, and increased sensitivity to radiation and chemical exposure.

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All GO Annotations

5
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

768
Tissues

51
cDNA Data

231
Literature Summary

3

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase ociad1

ZFIN ociad1

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All Sequences

120
RefSeq

39
UniProt

5
CCDS

CCDS19339.1, CCDS51518.1, CCDS80300.1

Ensembl

ENSMUSG00000029152 (Evidence)
NCBI Gene

68095

			Length	Strain/Species	Flank
genomic	ENSMUSG00000029152	Ensembl Gene Model \| MGI Sequence Detail	21286	C57BL/6J	± kb
transcript	ENSMUST00000031038	Ensembl \| MGI Sequence Detail	1523	Not Applicable
polypeptide	ENSMUSP00000031038	Ensembl \| MGI Sequence Detail	247	Not Applicable

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UniProt

5 Sequences
Protein Ontology

PR:000029660 OCIA domain-containing protein 1

(term hierarchy)
InterPro Domains

IPR040187 OCIA domain-containing protein 1/2

IPR009764 Ovarian carcinoma immunoreactive antigen domain
GlyGen

Q9CRD0 2 sites, 1 N-linked glycan (1 site), 1 O-linked glycan (1 site)

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All nucleic 239

Genomic 2

cDNA 234

Primer pair 3

Microarray probesets 5

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MGI:1927106, MGI:2140917, MGI:2141240, MGI:2141259, MGI:2441850

Summaries

All 397

Developmental Gene Expression 3

Diseases 1

Gene Ontology 3

Phenotypes 367
Earliest

J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
Latest

J:353367 Taketomi Y, et al., Lipid-orchestrated paracrine circuit coordinates mast cell maturation and anaphylaxis through functional interaction with fibroblasts. Immunity. 2024 Aug 13;57(8):1828-1847.e11

TSS for Ociad1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr46636	Chr5:73450137-73450162 (+)	23 bp
Tssr46637	Chr5:73450164-73450189 (+)	50 bp
Tssr1508	Chr5:73450207-73450218 (+)	86 bp
Tssr46638	Chr5:73450659-73450662 (+)	534 bp
Tssr46639	Chr5:73461956-73461980 (+)	11,841 bp
Tssr46640	Chr5:73464007-73464020 (+)	13,887 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24