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Cibar1 Gene Detail
Summary
  • Symbol
    Cibar1
  • Name
    CBY1 interacting BAR domain containing 1
  • Synonyms
    6720467C03Rik, Fam92a
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915349
    NCBI Gene: 68099
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:12153409-12172015 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 5.58 cM, cytoband A2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    561 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915349
 protein coding gene Chr4:12153142-12172047 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028063
 protein coding gene Chr4:8857463-8878292 (-)
A/J MGP_AJ_G0028020
 protein coding gene Chr4:8656083-8746330 (-)
AKR/J MGP_AKRJ_G0027986
 protein coding gene Chr4:8827413-8862187 (-)
BALB/cJ MGP_BALBcJ_G0028032
 protein coding gene Chr4:8652610-8686858 (-)
C3H/HeJ MGP_C3HHeJ_G0027762
 protein coding gene Chr4:9023603-9042169 (-)
C57BL/6NJ MGP_C57BL6NJ_G0028475
 protein coding gene Chr4:9214374-9303563 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0025816
 protein coding gene Chr4:8214336-8230755 (-)
CAST/EiJ MGP_CASTEiJ_G0027217
 protein coding gene Chr4:8827045-8845780 (-)
CBA/J MGP_CBAJ_G0027735
 protein coding gene Chr4:9552342-9570876 (-)
DBA/2J MGP_DBA2J_G0027878
 protein coding gene Chr4:8591085-8610371 (-)
FVB/NJ MGP_FVBNJ_G0027844
 protein coding gene Chr4:8404225-8422155 (-)
LP/J MGP_LPJ_G0027987
 protein coding gene Chr4:8990318-9010305 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0027877
 protein coding gene Chr4:9748232-9766295 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0028535
 protein coding gene Chr4:8828394-8854387 (-)
PWK/PhJ MGP_PWKPhJ_G0026937
 protein coding gene Chr4:8617001-8634563 (-)
SPRET/EiJ MGP_SPRETEiJ_G0026767
 protein coding gene Chr4:8798009-8814295 (-)
WSB/EiJ MGP_WSBEiJ_G0027295
 protein coding gene Chr4:8900006-8916382 (-)



Homology
more
  • Human Ortholog
    CIBAR1, CBY1 interacting BAR domain containing 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CIBAR1, CBY1 interacting BAR domain containing 1
  • Synonyms
    BARMR1, FAM92A, FAM92A1, PAPA9
  • Links
    NCBI Gene ID: 137392
    neXtProt AC: NX_A1XBS5
    UniProt: A1XBS5

  • Chr Location
    8q22.1; chr8:93698561-93731527 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with Cibar1 mouse models

Human Disease Mouse Models
      
IDs
 View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    18 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a knock-out allele exhibit decreased leukocyte cell number, abnormal digit morphology including metatarsal osteomas and polysyndactyly, tendon calcification, distinct abnormalities on the deltoid tuberosity of the humerus, and abnormal food intake that is specific to males.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    30
  • GO References
    9
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    713
  • Tissues
    3
  • cDNA Data
    44
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000028218 Ensembl Gene Model | MGI Sequence Detail 18607 C57BL/6J ±  kb
    transcript ENSMUST00000177837 Ensembl | MGI Sequence Detail 1325 Not Applicable  
    polypeptide ENSMUSP00000135961 Ensembl | MGI Sequence Detail 355 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      6 Sequences
    • Protein Ontology
      PR:000032451 CBY1-interacting BAR domain-containing protein 1
      (term hierarchy)
    • InterPro Domains
      IPR027267 AH/BAR domain superfamily
      IPR035590 CBY1-interacting BAR domain-containing protein 1/2, BAR domain
      IPR009602 CBY1-interacting BAR domain-containing protein/FAM92
    Molecular
    Reagents
    less
    • All nucleic 44
      cDNA 44

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:6393847
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 9
      Phenotypes 9
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:352092 Wang L, et al., Membrane remodeling by FAM92A1 during brain development regulates neuronal morphology, synaptic function, and cognition. Nat Commun. 2024 Jul 23;15(1):6209
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    12/10/2024
    MGI 6.24     		The Jackson Laboratory