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Nt5c3b Gene Detail
Summary
  • Symbol
    Nt5c3b
  • Name
    5'-nucleotidase, cytosolic IIIB
  • Synonyms
    2610037D24Rik, C330027I04Rik, Nt5c3l
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915356
    NCBI Gene: 68106
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:100313147-100332634 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 63.47 cM, cytoband D
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    559 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915356
 protein coding gene Chr11:100313143-100332634 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019155
 protein coding gene Chr11:103182013-103203256 (-)
A/J MGP_AJ_G0019123
 protein coding gene Chr11:98871478-98890922 (-)
AKR/J MGP_AKRJ_G0019092
 protein coding gene Chr11:101917642-101938107 (-)
BALB/cJ MGP_BALBcJ_G0019097
 protein coding gene Chr11:99350535-99369931 (-)
C3H/HeJ MGP_C3HHeJ_G0018906
 protein coding gene Chr11:102117088-102137299 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019546
 protein coding gene Chr11:106390290-106414085 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017172
 protein coding gene Chr11:96287532-96312315 (-)
CAST/EiJ MGP_CASTEiJ_G0018460
 protein coding gene Chr11:103087146-103108250 (-)
CBA/J MGP_CBAJ_G0018875
 protein coding gene Chr11:110812403-110834762 (-)
DBA/2J MGP_DBA2J_G0018987
 protein coding gene Chr11:98408819-98428233 (-)
FVB/NJ MGP_FVBNJ_G0018977
 protein coding gene Chr11:97940597-97961339 (-)
LP/J MGP_LPJ_G0019056
 protein coding gene Chr11:103728513-103751188 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019008
 protein coding gene Chr11:110426373-110445869 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019584
 protein coding gene Chr11:102261982-102281376 (-)
PWK/PhJ MGP_PWKPhJ_G0018223
 protein coding gene Chr11:99447317-99468237 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018015
 protein coding gene Chr11:101982319-102003007 (-)
WSB/EiJ MGP_WSBEiJ_G0018509
 protein coding gene Chr11:102246663-102266174 (-)



Homology
more
  • Human Ortholog
    NT5C3B, 5'-nucleotidase, cytosolic IIIB
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NT5C3B, 5'-nucleotidase, cytosolic IIIB
  • Synonyms
    cN-IIIB, CNIIIL, NT5C3L
  • Links
    NCBI Gene ID: 115024
    neXtProt AC: NX_Q969T7
    UniProt: Q969T7

  • Chr Location
    17q21.2; chr17:41825057-41836260 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    9
  • Endonuclease-mediated
    2
  • Gene trapped
    4
  • Targeted
    3
  • Genomic Mutations
    3 involving Nt5c3b
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    14 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    7
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    77
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000017176 Ensembl Gene Model | MGI Sequence Detail 19488 C57BL/6J ±  kb
transcript ENSMUST00000092688 Ensembl | MGI Sequence Detail 1399 Not Applicable  
polypeptide ENSMUSP00000090360 Ensembl | MGI Sequence Detail 300 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 77
    cDNA 77

    Microarray probesets 6
Other
Accession IDs
less
MGI:1917174, MGI:2144282
References
more
  • Summaries
    All 37
    Gene Ontology 5
    Phenotypes 11
  • Earliest
    J:50799 Liu P, et al., Embryonic lethality and tumorigenesis caused by segmental aneuploidy on mouse chromosome 11. Genetics. 1998 Nov;150(3):1155-68
  • Latest
    J:232020 Ermakova O, et al., Sensitized phenotypic screening identifies gene dosage sensitive region on chromosome 11 that predisposes to disease in mice. EMBO Mol Med. 2011 Jan;3(1):50-66
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory