About   Help   FAQ
Mtus2 Gene Detail
Summary
  • Symbol
    Mtus2
  • Name
    microtubule associated tumor suppressor candidate 2
  • Synonyms
    5730592G18Rik, A730013O20Rik, C130038G02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915388
    NCBI Gene: 77521
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:147894130-148252875 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 87.82 cM, cytoband G3
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    13633 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915388
 protein coding gene Chr5:147894085-148252875 (+)
129S1/SvImJ MGP_129S1SvImJ_G0030394
 protein coding gene Chr5:153666015-154048280 (+)
A/J MGP_AJ_G0030367
 protein coding gene Chr5:147142348-147483566 (+)
AKR/J MGP_AKRJ_G0030294
 protein coding gene Chr5:151659170-152046580 (+)
BALB/cJ MGP_BALBcJ_G0030376
 protein coding gene Chr5:148364562-148730844 (+)
C3H/HeJ MGP_C3HHeJ_G0030090
 protein coding gene Chr5:152638171-153013090 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030831
 protein coding gene Chr5:159314552-159714423 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0028044
 protein coding gene Chr5:141540786-141889723 (+)
CAST/EiJ MGP_CASTEiJ_G0029492
 protein coding gene Chr5:152222199-152592443 (+)
CBA/J MGP_CBAJ_G0030068
 protein coding gene Chr5:165954200-166384660 (+)
DBA/2J MGP_DBA2J_G0030212
 protein coding gene Chr5:146812600-147171828 (+)
FVB/NJ MGP_FVBNJ_G0030166
 protein coding gene Chr5:146018311-146384865 (+)
LP/J MGP_LPJ_G0030299
 protein coding gene Chr5:154353614-154740769 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0030202
 protein coding gene Chr5:168189391-168588274 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030861
 protein coding gene Chr5:151590185-151967421 (+)
PWK/PhJ MGP_PWKPhJ_G0029206
 protein coding gene Chr5:145934687-146297096 (+)
SPRET/EiJ MGP_SPRETEiJ_G0029042
 protein coding gene Chr5:148920443-149286504 (+)
WSB/EiJ MGP_WSBEiJ_G0029569
 protein coding gene Chr5:152393904-152775100 (+)



Homology
more
  • Human Ortholog
    MTUS2, microtubule associated scaffold protein 2
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MTUS2, microtubule associated scaffold protein 2
  • Synonyms
    CAZIP, ICIS, KIAA0774, TIP150
  • Links
    NCBI Gene ID: 23281
    neXtProt AC: NX_Q5JR59
    UniProt: Q5JR59

  • Chr Location
    13q12.3; chr13:28819963-29505947 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    972
  • Tissues
    111
  • cDNA Data
    27
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000029651 Ensembl Gene Model | MGI Sequence Detail 358746 C57BL/6J ±  kb
transcript ENSMUST00000085558 Ensembl | MGI Sequence Detail 7543 Not Applicable  
polypeptide ENSMUSP00000082694 Ensembl | MGI Sequence Detail 1353 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    7 Sequences
  • Protein Ontology
    PR:000030237 microtubule-associated tumor suppressor candidate 2
    (term hierarchy)
  • InterPro Domains
    IPR051293 Microtubule-associated tumor suppressor/Coiled-coil domain-containing protein 69
  • GlyGen
    Q3UHD3 3 sites, 2 N-linked glycans (3 sites)
Molecular
Reagents
less
  • All nucleic 35
    Genomic 1
    cDNA 28
    Primer pair 4
    Other 2

    Microarray probesets 6
Other
Accession IDs
less
MGI:1924771, MGI:2141097, MGI:2685609
References
more
  • Summaries
    All 32
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory