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Rpl39l Gene Detail
Summary
  • Symbol
    Rpl39l
  • Name
    ribosomal protein L39-like
  • Synonyms
    4930517K11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915422
    NCBI Gene: 68172
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:9988090-9992775 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 5.49 cM, cytoband A3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    182 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915422
 protein coding gene Chr16:9988061-9992775 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022502
 protein coding gene Chr16:6940249-6944923 (+)
A/J MGP_AJ_G0022464
 protein coding gene Chr16:6565666-6570346 (+)
AKR/J MGP_AKRJ_G0022440
 protein coding gene Chr16:6886710-6891391 (+)
BALB/cJ MGP_BALBcJ_G0022468
 protein coding gene Chr16:6705854-6710546 (+)
C3H/HeJ MGP_C3HHeJ_G0022235
 protein coding gene Chr16:6921283-6926683 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022917
 protein coding gene Chr16:7096920-7101598 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020438
 protein coding gene Chr16:6707052-6711739 (+)
CAST/EiJ MGP_CASTEiJ_G0021762
 protein coding gene Chr16:6956538-6961216 (+)
CBA/J MGP_CBAJ_G0022204
 protein coding gene Chr16:7376708-7381395 (+)
DBA/2J MGP_DBA2J_G0022335
 protein coding gene Chr16:6575828-6580514 (+)
FVB/NJ MGP_FVBNJ_G0022311
 protein coding gene Chr16:6562742-6567419 (+)
LP/J MGP_LPJ_G0022403
 protein coding gene Chr16:6906110-6910790 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022333
 protein coding gene Chr16:7122264-7126941 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022930
 protein coding gene Chr16:6824616-6830293 (+)
PWK/PhJ MGP_PWKPhJ_G0021502
 protein coding gene Chr16:6776203-6780881 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021332
 protein coding gene Chr16:6889549-6894240 (+)
WSB/EiJ MGP_WSBEiJ_G0021810
 protein coding gene Chr16:6889763-6894441 (+)



Homology
more
  • Human Ortholog
    RPL39L, ribosomal protein L39 like
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    RPL39L, ribosomal protein L39 like
  • Synonyms
    L39-2, RPL39L1
  • Links
    NCBI Gene ID: 116832
    neXtProt AC: NX_Q96EH5
    UniProt: Q96EH5

  • Chr Location
    3q27.3; chr3:187120948-187180908 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    15 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous null males exhibit reduced proliferation of spermatogonial stem cells, reduced sperm production, sperm morphology defects, and sub-fertility.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    766
  • Tissues
    25
  • cDNA Data
    35
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000039209 Ensembl Gene Model | MGI Sequence Detail 4686 C57BL/6J ±  kb
    transcript ENSMUST00000044103 Ensembl | MGI Sequence Detail 805 Not Applicable  
    polypeptide ENSMUSP00000041794 Ensembl | MGI Sequence Detail 51 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • PDB
      7CPV
    • InterPro Domains
      IPR000077 Large ribosomal subunit protein eL39
      IPR020083 Large ribosomal subunit protein eL39, conserved site
      IPR023626 Large ribosomal subunit protein eL39 domain superfamily
    Molecular
    Reagents
    less
    • All nucleic 38
      cDNA 35
      Primer pair 3

      Microarray probesets 3
    References
    more
    • Summaries
      All 25
      Developmental Gene Expression 3
      Gene Ontology 4
      Phenotypes 4
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:333015 Li H, et al., A male germ-cell-specific ribosome controls male fertility. Nature. 2022 Dec;612(7941):725-731
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory