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Inka1 Gene Detail
Summary
  • Symbol
    Inka1
  • Name
    inka box actin regulator 1
  • Synonyms
    6230427J02Rik, Fam212a, Inka1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915426
    NCBI Gene: 68176
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:107861422-107863078 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 59.07 cM, cytoband F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    81 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915426
 protein coding gene Chr9:107861422-107863078 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035278
 protein coding gene Chr9:109899159-109900814 (-)
A/J MGP_AJ_G0035257
 protein coding gene Chr9:105888290-105889946 (-)
AKR/J MGP_AKRJ_G0035189
 protein coding gene Chr9:108529201-108530857 (-)
BALB/cJ MGP_BALBcJ_G0035251
 protein coding gene Chr9:105558671-105560327 (-)
C3H/HeJ MGP_C3HHeJ_G0034961
 protein coding gene Chr9:108926745-108928401 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035771
 protein coding gene Chr9:112872051-112873707 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032669
 protein coding gene Chr9:103321639-103323297 (-)
CAST/EiJ MGP_CASTEiJ_G0034272
 protein coding gene Chr9:108884151-108885806 (-)
CBA/J MGP_CBAJ_G0034929
 protein coding gene Chr9:116870794-116872450 (-)
DBA/2J MGP_DBA2J_G0035090
 protein coding gene Chr9:105344286-105345942 (-)
FVB/NJ MGP_FVBNJ_G0035038
 protein coding gene Chr9:104109104-104110760 (-)
LP/J MGP_LPJ_G0035166
 protein coding gene Chr9:110094669-110096324 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035077
 protein coding gene Chr9:118463456-118465112 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035792
 protein coding gene Chr9:108806615-108808271 (-)
PWK/PhJ MGP_PWKPhJ_G0033979
 protein coding gene Chr9:105665021-105666677 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033814
 protein coding gene Chr9:108870840-108872495 (-)
WSB/EiJ MGP_WSBEiJ_G0034393
 protein coding gene Chr9:108686955-108688611 (-)



Homology
more
  • Human Ortholog
    INKA1, inka box actin regulator 1
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    INKA1, inka box actin regulator 1
  • Synonyms
    C3orf54, FAM212A, INCA
  • Links
    NCBI Gene ID: 389119
    neXtProt AC: NX_Q96EL1
    UniProt: Q96EL1

  • Chr Location
    3p21.31; chr3:49803261-49805030 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
A small percentage of homozygous null mice display exencephaly.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    806
  • Tissues
    54
  • cDNA Data
    21
  • Literature Summary
    5
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68176 NCBI Gene Model | MGI Sequence Detail 1657 C57BL/6J ±  kb
    transcript NM_026597 RefSeq | MGI Sequence Detail 1025 C57BL/6  
    polypeptide Q9CX62 UniProt | EBI | MGI Sequence Detail 282 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 24
      cDNA 21
      Primer pair 2
      Other 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:6155715
    References
    more
    • Summaries
      All 28
      Developmental Gene Expression 5
      Gene Ontology 4
      Phenotypes 4
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:330575 Yamada S, et al., Inka2, a novel Pak4 inhibitor, regulates actin dynamics in neuronal development. PLoS Genet. 2022 Oct;18(10):e1010438
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/19/2024
    MGI 6.24     		The Jackson Laboratory