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Krt42 Gene Detail
Summary
  • Symbol
    Krt42
  • Name
    keratin 42
  • Synonyms
    2410039E07Rik, ecat6, K17n, Ka22
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915489
    NCBI Gene: 68239
  • Alliance
    gene page
  • Transcription Start Sites
    8 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:100153708-100160697 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 63.44 cM, cytoband D
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    286 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915489
 protein coding gene Chr11:100153708-100160777 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019148
 protein coding gene Chr11:103021896-103028880 (-)
A/J MGP_AJ_G0019116
 protein coding gene Chr11:98697843-98704805 (-)
AKR/J MGP_AKRJ_G0019085
 protein coding gene Chr11:101741933-101748921 (-)
BALB/cJ MGP_BALBcJ_G0019090
 protein coding gene Chr11:99186140-99193123 (-)
C3H/HeJ MGP_C3HHeJ_G0018899
 protein coding gene Chr11:101932852-101939835 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019539
 protein coding gene Chr11:106190533-106197532 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017166
 protein coding gene Chr11:96126749-96133709 (-)
CAST/EiJ MGP_CASTEiJ_G0018453
 protein coding gene Chr11:102904379-102911344 (-)
CBA/J MGP_CBAJ_G0018868
 protein coding gene Chr11:110627005-110633988 (-)
DBA/2J MGP_DBA2J_G0018980
 protein coding gene Chr11:98247322-98254305 (-)
FVB/NJ MGP_FVBNJ_G0018970
 protein coding gene Chr11:97766977-97773960 (-)
LP/J MGP_LPJ_G0019049
 protein coding gene Chr11:103558569-103565549 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019001
 protein coding gene Chr11:110253071-110260054 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019577
 protein coding gene Chr11:102093675-102100658 (-)
PWK/PhJ MGP_PWKPhJ_G0018216
 protein coding gene Chr11:99274497-99281708 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018008
 protein coding gene Chr11:101799047-101806039 (-)
WSB/EiJ MGP_WSBEiJ_G0018502
 protein coding gene Chr11:102079585-102086557 (-)



Homology
less
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    4
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    718
  • Tissues
    12
  • cDNA Data
    6
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000053654 Ensembl Gene Model | MGI Sequence Detail 6990 C57BL/6J ±  kb
transcript ENSMUST00000017270 Ensembl | MGI Sequence Detail 1542 Not Applicable  
polypeptide ENSMUSP00000017270 Ensembl | MGI Sequence Detail 452 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 4
References
more
  • Summaries
    All 36
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 11
  • Earliest
    J:56548 Zheng B, et al., Engineering a mouse balancer chromosome. Nat Genet. 1999 Aug;22(4):375-8
  • Latest
    J:277277 Zieman AG, et al., Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma. Hum Mol Genet. 2019 Jul 1;28(13):2255-2270
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory