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Lypd2 Gene Detail
Summary
  • Symbol
    Lypd2
  • Name
    Ly6/Plaur domain containing 2
  • Synonyms
    0610005K03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915561
    NCBI Gene: 68311
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:74604096-74606178 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 34.26 cM, cytoband E1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    181 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915561
 protein coding gene Chr15:74604095-74606644 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021934
 protein coding gene Chr15:74514867-74516939 (-)
A/J MGP_AJ_G0021893
 protein coding gene Chr15:71856106-71858188 (-)
AKR/J MGP_AKRJ_G0021875
 protein coding gene Chr15:73696664-73698746 (-)
BALB/cJ MGP_BALBcJ_G0021900
 protein coding gene Chr15:71865149-71867231 (-)
C3H/HeJ MGP_C3HHeJ_G0021673
 protein coding gene Chr15:73850961-73853043 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022340
 protein coding gene Chr15:77331925-77334007 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019876
 protein coding gene Chr15:68268236-68270251 (-)
CAST/EiJ MGP_CASTEiJ_G0021192
 protein coding gene Chr15:74672848-74674970 (-)
CBA/J MGP_CBAJ_G0021639
 protein coding gene Chr15:79864572-79866654 (-)
DBA/2J MGP_DBA2J_G0021764
 protein coding gene Chr15:71454459-71456541 (-)
FVB/NJ MGP_FVBNJ_G0021746
 protein coding gene Chr15:70497782-70499864 (-)
LP/J MGP_LPJ_G0021836
 protein coding gene Chr15:74574020-74576102 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021769
 protein coding gene Chr15:85181620-85183676 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022361
 protein coding gene Chr15:74085299-74087355 (-)
PWK/PhJ MGP_PWKPhJ_G0020933
 protein coding gene Chr15:71560684-71562758 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020774
 protein coding gene Chr15:73973703-73975741 (-)
WSB/EiJ MGP_WSBEiJ_G0021244
 protein coding gene Chr15:74095945-74098001 (-)



Homology
more
  • Human Ortholog
    LYPD2, LY6/PLAUR domain containing 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    LYPD2, LY6/PLAUR domain containing 2
  • Synonyms
    LYPDC2, UNQ430
  • Links
    NCBI Gene ID: 137797
    neXtProt AC: NX_Q6UXB3
    UniProt: Q6UXB3

  • Chr Location
    8q24.3; chr8:142750150-142752532 (-)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    29 phenotype references
  • All Mutations and Alleles
    9
  • Chemically induced (other)
    3
  • Endonuclease-mediated
    1
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    5 involving Lypd2
  • Find Mice (IMSR)
    13 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    2
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    4
  • cDNA Data
    11
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022595 Ensembl Gene Model | MGI Sequence Detail 2083 C57BL/6J ±  kb
transcript ENSMUST00000023260 Ensembl | MGI Sequence Detail 513 Not Applicable  
polypeptide ENSMUSP00000023260 Ensembl | MGI Sequence Detail 127 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 2
References
more
  • Summaries
    All 50
    Developmental Gene Expression 1
    Diseases 1
    Gene Ontology 2
    Phenotypes 29
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:348039 Mandula JK, et al., Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages. Immunity. 2024 Apr 11;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory