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Pdrg1 Gene Detail
Summary
  • Symbol
    Pdrg1
  • Name
    p53 and DNA damage regulated 1
  • Synonyms
    1110004D19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915809
    NCBI Gene: 68559
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:152850810-152857347 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 2, 75.41 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    281 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915809
protein coding gene Chr2:152850810-152857939 (-)
129S1/SvImJ MGP_129S1SvImJ_G0026684
protein coding gene Chr2:157617460-157623997 (-)
A/J MGP_AJ_G0026650
protein coding gene Chr2:151310676-151317238 (-)
AKR/J MGP_AKRJ_G0026620
protein coding gene Chr2:155733853-155740390 (-)
BALB/cJ MGP_BALBcJ_G0026659
protein coding gene Chr2:151620610-151627150 (-)
C3H/HeJ MGP_C3HHeJ_G0026402
protein coding gene Chr2:156103060-156115104 (-)
C57BL/6NJ MGP_C57BL6NJ_G0027108
protein coding gene Chr2:162189915-162196452 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0024479
protein coding gene Chr2:144899250-144905964 (-)
CAST/EiJ MGP_CASTEiJ_G0025863
protein coding gene Chr2:156365129-156371699 (-)
CBA/J MGP_CBAJ_G0026380
protein coding gene Chr2:168154858-168161398 (-)
DBA/2J MGP_DBA2J_G0026516
protein coding gene Chr2:150517364-150528537 (-)
FVB/NJ MGP_FVBNJ_G0026482
protein coding gene Chr2:148985274-148991814 (-)
LP/J MGP_LPJ_G0026620
protein coding gene Chr2:157765204-157771741 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0026503
protein coding gene Chr2:172221542-172228201 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0027164
protein coding gene Chr2:155629520-155636057 (-)
PWK/PhJ MGP_PWKPhJ_G0025597
protein coding gene Chr2:150053869-150060417 (-)
SPRET/EiJ MGP_SPRETEiJ_G0025400
protein coding gene Chr2:154462804-154469380 (-)
WSB/EiJ MGP_WSBEiJ_G0025933
protein coding gene Chr2:156531483-156539289 (-)



Homology
more
  • Human Ortholog
    PDRG1, p53 and DNA damage regulated 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PDRG1, p53 and DNA damage regulated 1
  • Synonyms
    C20orf126, PDRG
  • Links
    NCBI Gene ID: 81572
    neXtProt AC: NX_Q9NUG6
    UniProt: Q9NUG6

  • Chr Location
    20q11.21; chr20:31944337-31952046 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000027472 Ensembl Gene Model | MGI Sequence Detail 6538 C57BL/6J ±  kb
transcript ENSMUST00000028972 Ensembl | MGI Sequence Detail 1273 Not Applicable  
polypeptide ENSMUSP00000028972 Ensembl | MGI Sequence Detail 133 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 82
    cDNA 82

    Microarray probesets 6
Other
Accession IDs
less
MGI:2139188, MGI:2139234
References
more
  • Summaries
    All 31
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:348634 Lin L, et al., Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size. Neuron. 2024 Apr 22;

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory