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Mrpl28 Gene Detail
Summary
  • Symbol
    Mrpl28
  • Name
    mitochondrial ribosomal protein L28
  • Synonyms
    1110015G04Rik, MAAT1, p15
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915861
    NCBI Gene: 68611
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:26342477-26345587 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 13.07 cM, cytoband B1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    188 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915861
 protein coding gene Chr17:26342474-26345587 (+)
129S1/SvImJ MGP_129S1SvImJ_G0023391
 protein coding gene Chr17:25260614-25263701 (+)
A/J MGP_AJ_G0023350
 protein coding gene Chr17:24513527-24516616 (+)
AKR/J MGP_AKRJ_G0023316
 protein coding gene Chr17:24621028-24624122 (+)
BALB/cJ MGP_BALBcJ_G0023355
 protein coding gene Chr17:24734111-24737204 (+)
C3H/HeJ MGP_C3HHeJ_G0023115
 protein coding gene Chr17:25012504-25015583 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023797
 protein coding gene Chr17:26329340-26332516 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0021273
 protein coding gene Chr17:21970328-21973456 (+)
CAST/EiJ MGP_CASTEiJ_G0022617
 protein coding gene Chr17:24913740-24918183 (+)
CBA/J MGP_CBAJ_G0023090
 protein coding gene Chr17:27260117-27263210 (+)
DBA/2J MGP_DBA2J_G0023220
 protein coding gene Chr17:24107401-24110394 (+)
FVB/NJ MGP_FVBNJ_G0023190
 protein coding gene Chr17:23869260-23872352 (+)
LP/J MGP_LPJ_G0023297
 protein coding gene Chr17:25543005-25547428 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0023209
 protein coding gene Chr17:26830663-26833754 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023837
 protein coding gene Chr17:24968612-24971703 (+)
PWK/PhJ MGP_PWKPhJ_G0022366
 protein coding gene Chr17:22875676-22878953 (+)
SPRET/EiJ MGP_SPRETEiJ_G0022184
 protein coding gene Chr17:23034789-23038919 (+)
WSB/EiJ MGP_WSBEiJ_G0022680
 protein coding gene Chr17:24993808-24996902 (+)



Homology
more
  • Human Ortholog
    MRPL28, mitochondrial ribosomal protein L28
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRPL28, mitochondrial ribosomal protein L28
  • Synonyms
    bL28m, MAAT1, p15
  • Links
    NCBI Gene ID: 10573
    neXtProt AC: NX_Q13084
    UniProt: Q13084

  • Chr Location
    16p13.3; chr16:366969-371289 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    10 phenotype references
  • All Mutations and Alleles
    13
  • Endonuclease-mediated
    1
  • Gene trapped
    7
  • Radiation induced
    2
  • Targeted
    3
  • Genomic Mutations
    2 involving Mrpl28
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    14 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    759
  • Tissues
    17
  • cDNA Data
    110
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 68611 NCBI Gene Model | MGI Sequence Detail 3111 C57BL/6J ±  kb
transcript NM_024227 RefSeq | MGI Sequence Detail 1080 C57BL/6  
polypeptide Q9D1B9 UniProt | EBI | MGI Sequence Detail 257 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000010589 large ribosomal subunit protein bL28m
    (term hierarchy)
  • InterPro Domains
    IPR026569 Large ribosomal subunit protein bL28
    IPR034704 Large ribosomal subunit protein bL28/bL31-like superfamily
    IPR037147 Large ribosomal subunit protein bL28 superfamily
  • GlyGen
    Q9D1B9 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 111
    cDNA 110
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 40
    Developmental Gene Expression 2
    Gene Ontology 8
    Phenotypes 10
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:297050 Cheong A, et al., Expression analysis of mammalian mitochondrial ribosomal protein genes. Gene Expr Patterns. 2020 Sep 25;38:119147
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory