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Fbxw9 Gene Detail
Summary
  • Symbol
    Fbxw9
  • Name
    F-box and WD-40 domain protein 9
  • Synonyms
    1110017H11Rik, Fbw9
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915878
    NCBI Gene: 68628
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:85786748-85793750 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 8, 41.54 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    246 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915878
protein coding gene Chr8:85786684-85793753 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033890
protein coding gene Chr8:86006824-86013776 (+)
A/J MGP_AJ_G0033873
protein coding gene Chr8:82607466-82615554 (+)
AKR/J MGP_AKRJ_G0033799
protein coding gene Chr8:85065689-85072643 (+)
BALB/cJ MGP_BALBcJ_G0033866
protein coding gene Chr8:82744053-82751007 (+)
C3H/HeJ MGP_C3HHeJ_G0033576
protein coding gene Chr8:85684359-85691308 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034386
protein coding gene Chr8:89296465-89305132 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031327
protein coding gene Chr8:76411371-76418736 (+)
CAST/EiJ MGP_CASTEiJ_G0032906
protein coding gene Chr8:85115756-85122377 (+)
CBA/J MGP_CBAJ_G0033552
protein coding gene Chr8:92328958-92335911 (+)
DBA/2J MGP_DBA2J_G0033705
protein coding gene Chr8:82247190-82254143 (+)
FVB/NJ MGP_FVBNJ_G0033653
protein coding gene Chr8:81206535-81213395 (+)
LP/J MGP_LPJ_G0033797
protein coding gene Chr8:86109721-86118558 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033695
protein coding gene Chr8:94890468-94897413 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034403
protein coding gene Chr8:85054497-85061300 (+)
PWK/PhJ MGP_PWKPhJ_G0032609
protein coding gene Chr8:81493906-81501201 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032446
protein coding gene Chr8:83874052-83881156 (+)
WSB/EiJ MGP_WSBEiJ_G0033019
protein coding gene Chr8:85480623-85488692 (+)



Homology
more
  • Human Ortholog
    FBXW9, F-box and WD repeat domain containing 9
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    FBXW9, F-box and WD repeat domain containing 9
  • Synonyms
    Fbw9, MEC-15
  • Links
    NCBI Gene ID: 84261
    neXtProt AC: NX_Q5XUX1
    UniProt: Q5XUX1

  • Chr Location
    19p13.13; chr19:12688053-12696631 (-)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotypes from 2 alleles in 2 genetic backgrounds
    42 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 68628 NCBI Gene Model | MGI Sequence Detail 7003 C57BL/6J ±  kb
    transcript NM_026791 RefSeq | MGI Sequence Detail 1866 C57BL/6  
    polypeptide NP_081067 RefSeq | MGI Sequence Detail 458 C57BL/6  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 51
      cDNA 51

      Microarray probesets 5
    References
    more
    • Summaries
      All 65
      Developmental Gene Expression 1
      Phenotypes 42
    • Earliest
      J:13049 Gruneberg H, Genetical studies on the skeleton of the mouse. XVIII. Three genes for syndactylism. J Genet. 1956;54(1):113-145
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.
    last database update
    12/10/2024
    MGI 6.24
    The Jackson Laboratory