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Pga5 Gene Detail
Summary
  • Symbol
    Pga5
  • Name
    pepsinogen 5, group I
  • Synonyms
    1110035E17Rik, Pepf, pepsinogen A5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915935
    NCBI Gene: 58803
  • Alliance
  • Transcription Start Sites
    17 TSS
Location &
Maps
more
  • Sequence Map
    Chr19:10646321-10655435 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 19, 7.12 cM, cytoband B
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    416 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915935
protein coding gene Chr19:10646320-10655435 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024854
protein coding gene Chr19:8025406-8042397 (-)
A/J MGP_AJ_G0024822
protein coding gene Chr19:7484320-7499608 (-)
AKR/J MGP_AKRJ_G0024797
protein coding gene Chr19:7778630-7794286 (-)
BALB/cJ MGP_BALBcJ_G0024822
protein coding gene Chr19:7525717-7541846 (-)
C3H/HeJ MGP_C3HHeJ_G0024588
protein coding gene Chr19:7669208-7691326 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025270
protein coding gene Chr19:8382425-8399739 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022697
protein coding gene Chr19:7901506-7918960 (-)
CAST/EiJ MGP_CASTEiJ_G0024061
protein coding gene Chr19:7312306-7330136 (-)
CBA/J MGP_CBAJ_G0024562
protein coding gene Chr19:8430918-8446280 (-)
DBA/2J MGP_DBA2J_G0024689
protein coding gene Chr19:7490975-7506338 (-)
FVB/NJ MGP_FVBNJ_G0024656
protein coding gene Chr19:7535048-7551263 (-)
LP/J MGP_LPJ_G0024776
protein coding gene Chr19:7985122-8001734 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024683
protein coding gene Chr19:8332048-8348728 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0025318
protein coding gene Chr19:7791728-7808719 (-)
PWK/PhJ MGP_PWKPhJ_G0023806
protein coding gene Chr19:6934660-6950823 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023611
protein coding gene Chr19:6971154-6987772 (-)
WSB/EiJ MGP_WSBEiJ_G0024123
protein coding gene Chr19:7686822-7706537 (-)



Homology
more
  • Human Ortholog
    PGA3, pepsinogen A3
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PGA3, pepsinogen A3
  • Links
    NCBI Gene ID: 643834
    neXtProt AC: NX_P0DJD8
    UniProt: P0DJD8

  • Chr Location
    11q12.2; chr11:61203307-61213098 (+)  GRCh38


  • Human Ortholog
    PGA5, pepsinogen A5
  • Synonyms
    Pg5
  • Links
    NCBI Gene ID: 5222
    neXtProt AC: NX_P0DJD9
    UniProt: P0DJD9

  • Chr Location
    11q12.2; chr11:61241175-61251444 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 58803 NCBI Gene Model | MGI Sequence Detail 9115 C57BL/6J ±  kb
transcript NM_021453 RefSeq | MGI Sequence Detail 1416 C57BL/6  
polypeptide Q9D106 UniProt | EBI | MGI Sequence Detail 387 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 16
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 33
    Developmental Gene Expression 5
    Gene Ontology 4
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:331869 Shi W, et al., Glypican-6 and Glypican-4 stimulate embryonic stomach growth by regulating Hedgehog and noncanonical Wnt signaling. Dev Dyn. 2022 Dec;251(12):2015-2028

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory