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Zfp740 Gene Detail
Summary
  • Symbol
    Zfp740
  • Name
    zinc finger protein 740
  • Synonyms
    1110034O07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1915994
    NCBI Gene: 68744
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:102112080-102124045 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 15, 57.37 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    306 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1915994
protein coding gene Chr15:102111684-102124045 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022403
protein coding gene Chr15:104358401-104371747 (+)
A/J MGP_AJ_G0022365
protein coding gene Chr15:100263315-100275035 (+)
AKR/J MGP_AKRJ_G0022340
protein coding gene Chr15:103295050-103307032 (+)
BALB/cJ MGP_BALBcJ_G0022369
protein coding gene Chr15:100307711-100319439 (+)
C3H/HeJ MGP_C3HHeJ_G0022136
protein coding gene Chr15:103372934-103384609 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022818
protein coding gene Chr15:108238731-108251663 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020341
protein coding gene Chr15:96039616-96051119 (+)
CAST/EiJ MGP_CASTEiJ_G0021662
protein coding gene Chr15:104233994-104245638 (+)
CBA/J MGP_CBAJ_G0022105
protein coding gene Chr15:112032809-112047113 (+)
DBA/2J MGP_DBA2J_G0022236
protein coding gene Chr15:99551038-99563143 (+)
FVB/NJ MGP_FVBNJ_G0022212
protein coding gene Chr15:98612420-98624087 (+)
LP/J MGP_LPJ_G0022305
protein coding gene Chr15:104520348-104533880 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022234
protein coding gene Chr15:115613774-115626444 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022830
protein coding gene Chr15:103321279-103332994 (+)
PWK/PhJ MGP_PWKPhJ_G0021402
protein coding gene Chr15:99700786-99713319 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021234
protein coding gene Chr15:103171876-103183605 (+)
WSB/EiJ MGP_WSBEiJ_G0021712
protein coding gene Chr15:103953323-103966090 (+)



Homology
more
  • Human Ortholog
    ZNF740, zinc finger protein 740
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ZNF740, zinc finger protein 740
  • Synonyms
    Zfp740
  • Links
    NCBI Gene ID: 283337
    neXtProt AC: NX_Q8NDX6
    UniProt: Q8NDX6

  • Chr Location
    12q13.13; chr12:53180704-53195142 (+)  GRCh38

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    25 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 68744 NCBI Gene Model | MGI Sequence Detail 11966 C57BL/6J ±  kb
transcript NM_001358674 RefSeq | MGI Sequence Detail 4382 C57BL/6  
polypeptide Q6NZQ6 UniProt | EBI | MGI Sequence Detail 180 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 12
    cDNA 11
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2146230
References
more
  • Summaries
    All 51
    Developmental Gene Expression 4
    Diseases 1
    Gene Ontology 4
    Phenotypes 25
  • Earliest
    J:7688 Lane PW, et al., Association of megacolon with a new dominant spotting gene (Dom) in the mouse. J Hered. 1984 Nov-Dec;75(6):435-9
  • Latest
    J:342387 Nabekura T, et al., Themis2 regulates natural killer cell memory function and formation. Nat Commun. 2023 Nov 8;14(1):7200

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory