About   Help   FAQ
Dtwd2 Gene Detail
Summary
  • Symbol
    Dtwd2
  • Name
    DTW domain containing 2
  • Synonyms
    1190002H09Rik, 8030470C17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916107
    NCBI Gene: 68857
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr18:49829212-49888668 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 18, 27.09 cM, cytoband C
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1422 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916107
 protein coding gene Chr18:49829212-49890255 (-)
129S1/SvImJ MGP_129S1SvImJ_G0024418
 protein coding gene Chr18:48671472-48740579 (-)
A/J MGP_AJ_G0024384
 protein coding gene Chr18:46853292-46913204 (-)
AKR/J MGP_AKRJ_G0024354
 protein coding gene Chr18:48143431-48211074 (-)
BALB/cJ MGP_BALBcJ_G0024384
 protein coding gene Chr18:46973081-47038553 (-)
C3H/HeJ MGP_C3HHeJ_G0024151
 protein coding gene Chr18:48272563-48337953 (-)
C57BL/6NJ MGP_C57BL6NJ_G0024830
 protein coding gene Chr18:50332384-50398600 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0022263
 protein coding gene Chr18:46557860-46621624 (-)
CAST/EiJ MGP_CASTEiJ_G0023626
 protein coding gene Chr18:48255440-48327714 (-)
CBA/J MGP_CBAJ_G0024121
 protein coding gene Chr18:51764712-51839383 (-)
DBA/2J MGP_DBA2J_G0024251
 protein coding gene Chr18:46483501-46543181 (-)
FVB/NJ MGP_FVBNJ_G0024218
 protein coding gene Chr18:46048018-46107726 (-)
LP/J MGP_LPJ_G0024336
 protein coding gene Chr18:48698639-48761807 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0024248
 protein coding gene Chr18:53282475-53364001 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0024877
 protein coding gene Chr18:48106716-48172400 (-)
PWK/PhJ MGP_PWKPhJ_G0023369
 protein coding gene Chr18:46614978-46676738 (-)
SPRET/EiJ MGP_SPRETEiJ_G0023175
 protein coding gene Chr18:48325191-48396635 (-)
WSB/EiJ MGP_WSBEiJ_G0023689
 protein coding gene Chr18:47995738-48061398 (-)



Homology
more
  • Human Ortholog
    DTWD2, DTW domain containing 2
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DTWD2, DTW domain containing 2
  • Links
    NCBI Gene ID: 285605
    neXtProt AC: NX_Q8NBA8
    UniProt: Q8NBA8

  • Chr Location
    5q23.1; chr5:118836074-118988547 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    11
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000024505 Ensembl Gene Model | MGI Sequence Detail 59457 C57BL/6J ±  kb
transcript ENSMUST00000163590 Ensembl | MGI Sequence Detail 3145 Not Applicable  
polypeptide ENSMUSP00000128219 Ensembl | MGI Sequence Detail 298 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    Genomic 2
    cDNA 11

    Microarray probesets 4
Other
Accession IDs
less
MGI:2147217, MGI:2147385
References
more
  • Summaries
    All 34
    Gene Ontology 3
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:327181 Lewis MA, et al., Identification and characterisation of spontaneous mutations causing deafness from a targeted knockout programme. BMC Biol. 2022 Mar 17;20(1):67
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory