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Tmem121 Gene Detail
Summary
  • Symbol
    Tmem121
  • Name
    transmembrane protein 121
  • Synonyms
    2410008J05Rik, Hole
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916445
    NCBI Gene: 69195
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:113149550-113153143 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 12, 61.76 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    70 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916445
 protein coding gene Chr12:113149523-113153143 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020175
 protein coding gene Chr12:115684439-115688040 (+)
A/J MGP_AJ_G0020131
 protein coding gene Chr12:111206181-111209767 (+)
AKR/J MGP_AKRJ_G0020106
 protein coding gene Chr12:114442382-114446017 (+)
BALB/cJ MGP_BALBcJ_G0020116
 protein coding gene Chr12:111671071-111674671 (+)
C3H/HeJ MGP_C3HHeJ_G0019918
 protein coding gene Chr12:114962671-114966260 (+)
C57BL/6NJ MGP_C57BL6NJ_G0020561
 protein coding gene Chr12:119227219-119230812 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018175
 protein coding gene Chr12:107637229-107640829 (+)
CAST/EiJ MGP_CASTEiJ_G0019458
 protein coding gene Chr12:109808191-109811770 (+)
CBA/J MGP_CBAJ_G0019885
 protein coding gene Chr12:123806989-123810574 (+)
DBA/2J MGP_DBA2J_G0020002
 protein coding gene Chr12:110708898-110712477 (+)
FVB/NJ MGP_FVBNJ_G0019987
 protein coding gene Chr12:109551597-109555829 (+)
LP/J MGP_LPJ_G0020076
 protein coding gene Chr12:115502240-115505832 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020025
 protein coding gene Chr12:126882821-126886414 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0020590
 protein coding gene Chr12:113953208-113956804 (+)
PWK/PhJ MGP_PWKPhJ_G0019220
 protein coding gene Chr12:105368817-105372451 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019024
 protein coding gene Chr12:108141690-108145303 (+)
WSB/EiJ MGP_WSBEiJ_G0019518
 protein coding gene Chr12:114867112-114870663 (+)



Homology
more
  • Human Ortholog
    TMEM121, transmembrane protein 121
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMEM121, transmembrane protein 121
  • Synonyms
    hhole, hole, TMEM121A
  • Links
    NCBI Gene ID: 80757
    neXtProt AC: NX_Q9BTD3
    UniProt: Q9BTD3

  • Chr Location
    14q32.33; chr14:105526583-105530198 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    724
  • Tissues
    10
  • cDNA Data
    10
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000049036 Ensembl Gene Model | MGI Sequence Detail 3594 C57BL/6J ±  kb
transcript ENSMUST00000058491 Ensembl | MGI Sequence Detail 1574 Not Applicable  
polypeptide ENSMUSP00000055994 Ensembl | MGI Sequence Detail 318 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 2
References
more
  • Summaries
    All 22
    Developmental Gene Expression 1
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory