Ptms MGI Mouse Gene Detail - MGI:1916452

Symbol

Ptms
Name

parathymosin
Synonyms

2610009E16Rik

Feature Type

protein coding gene
IDs

MGI:1916452
NCBI Gene: 69202
Alliance

gene page
Transcription Start Sites

19 TSS

Sequence Map

Chr6:124890638-124894909 bp, - strand
From NCBI annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 6, 59.17 cM, cytoband F2
Mapping Data

2 experiments

SNPs within 2kb

110 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1916452	protein coding gene	Chr6:124890638-124897066 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0031277	protein coding gene	Chr6:128229000-128235449 (-)
A/J	MGP_AJ_G0031247	protein coding gene	Chr6:123399581-123406002 (-)
AKR/J	MGP_AKRJ_G0031175	protein coding gene	Chr6:126767854-126774275 (-)
BALB/cJ	MGP_BALBcJ_G0031255	protein coding gene	Chr6:123000313-123006731 (-)
C3H/HeJ	MGP_C3HHeJ_G0030978	protein coding gene	Chr6:126817037-126823816 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0031711	protein coding gene	Chr6:131608856-131618990 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0028861	protein coding gene	Chr6:120611411-120617781 (-)
CAST/EiJ	MGP_CASTEiJ_G0030359	protein coding gene	Chr6:127030014-127036398 (-)
CBA/J	MGP_CBAJ_G0030939	protein coding gene	Chr6:136643880-136650316 (-)
DBA/2J	MGP_DBA2J_G0031095	protein coding gene	Chr6:122329048-122335828 (-)
FVB/NJ	MGP_FVBNJ_G0031045	protein coding gene	Chr6:121230808-121239236 (-)
LP/J	MGP_LPJ_G0031175	protein coding gene	Chr6:128398228-128404650 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0031083	protein coding gene	Chr6:140695507-140701927 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0031746	protein coding gene	Chr6:126658729-126666324 (-)
PWK/PhJ	MGP_PWKPhJ_G0030074	protein coding gene	Chr6:120560225-120566632 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0029903	protein coding gene	Chr6:124745758-124752080 (-)
WSB/EiJ	MGP_WSBEiJ_G0030444	protein coding gene	Chr6:127024045-127030462 (-)

Human Ortholog

PTMS, parathymosin

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

PTMS, parathymosin
Synonyms

ParaT
Links

HGNC:9629

NCBI Gene ID: 5763

neXtProt AC: NX_P20962

UniProt: P20962
Chr Location

12p13.31; chr12:6765516-6770952 (+) GRCh38

MGI Vertebrate Homology

Ptms stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: PTMS
Gene Tree

Ptms

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Phenotype Summary

7 phenotypes from 1 allele in 1 genetic background
10 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

17
Gene trapped

14
Targeted

3
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

11 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

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All GO Annotations

6
GO References

3

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

763
Tissues

50
cDNA Data

178
Literature Summary

4

Images

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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All Sequences

38
RefSeq

2
UniProt

2
CCDS

CCDS39630.1

Ensembl

ENSMUSG00000030122 (Evidence)
NCBI Gene

69202

			Length	Strain/Species	Flank
genomic	69202	NCBI Gene Model \| MGI Sequence Detail	4272	C57BL/6J	± kb
transcript	NM_026988	RefSeq \| MGI Sequence Detail	1155	C57BL/6
polypeptide	Q9D0J8	UniProt \| EBI \| MGI Sequence Detail	101	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000013437 parathymosin

(term hierarchy)
InterPro Domains

IPR004931 Prothymosin/parathymosin

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All nucleic 178

cDNA 178

Microarray probesets 5

Summaries

All 39

Developmental Gene Expression 4

Gene Ontology 3

Phenotypes 10
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Ptms:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr63231	Chr6:124894902-124894918 (-)	-1 bp
Tssr2013	Chr6:124894858-124894862 (-)	49 bp
Tssr63230	Chr6:124894719-124894725 (-)	187 bp
Tssr63229	Chr6:124892535-124892578 (-)	2,352 bp
Tssr63228	Chr6:124891902-124891938 (-)	2,989 bp
Tssr63227	Chr6:124891639-124891657 (-)	3,261 bp
Tssr63226	Chr6:124891399-124891421 (-)	3,499 bp
Tssr63225	Chr6:124891185-124891197 (-)	3,718 bp
Tssr63224	Chr6:124891169-124891176 (-)	3,736 bp
Tssr63223	Chr6:124891149-124891162 (-)	3,753 bp
Tssr63222	Chr6:124891074-124891093 (-)	3,825 bp
Tssr63221	Chr6:124891054-124891070 (-)	3,847 bp
Tssr63220	Chr6:124891024-124891028 (-)	3,883 bp
Tssr63219	Chr6:124891016-124891020 (-)	3,891 bp
Tssr63218	Chr6:124890998-124891007 (-)	3,906 bp
Tssr63217	Chr6:124890969-124890984 (-)	3,932 bp
Tssr63216	Chr6:124890932-124890957 (-)	3,964 bp
Tssr63215	Chr6:124890908-124890918 (-)	3,996 bp
Tssr63214	Chr6:124890821-124890849 (-)	4,074 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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