Teshl Gene Detail

Summary

• Symbol
  Teshl
• Name
  testicular germ cell expressed HSF2 interacting lncRNA
• Synonyms
  1700027A15Rik

• Feature Type
  lncRNA gene
• IDs
  MGI:1916699
  NCBI Gene: 69449
• Alliance
  gene page
• Transcription Start Sites
  2 TSS

Location &
Maps

• Sequence Map
  Chr1:73055195-73064667 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 1, 36.94 cM
• Mapping Data
  1 experiment

Strain
Comparison

• SNPs within 2kb
  318 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1916699	lncRNA gene	Chr1:73024003-73064667 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0002699	antisense lncRNA gene	Chr1:73534441-73579772 (+)
A/J	MGP_AJ_G0002675	antisense lncRNA gene	Chr1:70953321-70993810 (+)
AKR/J	MGP_AKRJ_G0002655	antisense lncRNA gene	Chr1:72933371-72977470 (+)
BALB/cJ	MGP_BALBcJ_G0002661	antisense lncRNA gene	Chr1:71015763-71058470 (+)
C3H/HeJ	MGP_C3HHeJ_G0002621	antisense lncRNA gene	Chr1:73248891-73291966 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0002805	antisense lncRNA gene	Chr1:76380482-76423184 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0002352	antisense lncRNA gene	Chr1:66586994-66626128 (+)
CAST/EiJ	MGP_CASTEiJ_G0002593	antisense lncRNA gene	Chr1:72558504-72596741 (+)
CBA/J	MGP_CBAJ_G0002616	antisense lncRNA gene	Chr1:78878966-78930822 (+)
DBA/2J	MGP_DBA2J_G0002621	antisense lncRNA gene	Chr1:70286673-70327025 (+)
FVB/NJ	MGP_FVBNJ_G0002641	antisense lncRNA gene	Chr1:69466683-69507576 (+)
LP/J	MGP_LPJ_G0002701	antisense lncRNA gene	Chr1:74590712-74635768 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0002631	antisense lncRNA gene	Chr1:82313715-82357686 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0002810	antisense lncRNA gene	Chr1:72965372-73005193 (+)
PWK/PhJ	MGP_PWKPhJ_G0002551	antisense lncRNA gene	Chr1:69763988-69773142 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0002505	antisense lncRNA gene	Chr1:72312019-72352661 (+)
WSB/EiJ	MGP_WSBEiJ_G0002623	antisense lncRNA gene	Chr1:72788587-72829535 (+)

Homology

• Gene Tree
  Teshl
  

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  2 phenotypes from 1 allele in 1 genetic background
  5 phenotype references
  

• All Mutations and Alleles
  3
• Chemically induced (other)
  1
• Endonuclease-mediated
  1
• Radiation induced
  1
• Genomic Mutations
  2 involving Teshl
• Find Mice (IMSR)
  1 strains or lines available
• Comparison Matrix
  Gene Expression + Phenotype

Mice homozygous for a null allele exhibit reduced fertility associated with fewer female offspring and abnormal sperm head morphology.

Gene Ontology
(GO)
Classifications

Expression

• Assay Results
  706
• cDNA Data
  3

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

• Other Mouse Links
  GEO
  Expression Atlas

Sequences &
Gene Models

• All Sequences
  31
• RefSeq
  2

• Ensembl
  ENSMUSG00000101968 (Evidence)
• NCBI Gene
  69449

Representative Sequences			Length	Strain/Species
genomic	69449	NCBI Gene Model | MGI Sequence Detail	9473	C57BL/6J
transcript	NR_038002	RefSeq | MGI Sequence Detail	416	C57BL/6

Molecular
Reagents

• All nucleic 3

  cDNA 3

  
  

  Microarray probesets 1

Other
Accession IDs

MGI:7444817

References

• Summaries
  All 14

  Phenotypes 5
• Earliest
  J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
• Latest
  J:307510 Hong SH, et al., Testicular germ cell-specific lncRNA, Teshl, is required for complete expression of Y chromosome genes and a normal offspring sex ratio. Sci Adv. 2021 Jun;7(24)

TSS for Teshl:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr7350	Chr1:73063744-73063749 (+)	8,552 bp
Tssr7351	Chr1:73063762-73063780 (+)	8,576 bp