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Tmco2 Gene Detail
Summary
  • Symbol
    Tmco2
  • Name
    transmembrane and coiled-coil domains 2
  • Synonyms
    1700028F16Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916719
    NCBI Gene: 69469
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:120962848-120966414 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 56.80 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    151 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916719
 protein coding gene Chr4:120962848-120966423 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028721
 protein coding gene Chr4:122413996-122417571 (-)
A/J MGP_AJ_G0028681
 protein coding gene Chr4:117577696-117581271 (-)
AKR/J MGP_AKRJ_G0028634
 protein coding gene Chr4:120180996-120184571 (-)
BALB/cJ MGP_BALBcJ_G0028704
 protein coding gene Chr4:118198233-118201808 (-)
C3H/HeJ MGP_C3HHeJ_G0028419
 protein coding gene Chr4:121700588-121704163 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029145
 protein coding gene Chr4:127019320-127022895 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026422
 protein coding gene Chr4:111619371-111623591 (-)
CAST/EiJ MGP_CASTEiJ_G0027850
 protein coding gene Chr4:119073875-119077450 (-)
CBA/J MGP_CBAJ_G0028386
 protein coding gene Chr4:130473294-130476869 (-)
DBA/2J MGP_DBA2J_G0028533
 protein coding gene Chr4:118160496-118164071 (-)
FVB/NJ MGP_FVBNJ_G0028499
 protein coding gene Chr4:116678075-116681650 (-)
LP/J MGP_LPJ_G0028633
 protein coding gene Chr4:122537038-122540613 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028527
 protein coding gene Chr4:135274786-135278361 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029182
 protein coding gene Chr4:121245623-121249198 (-)
PWK/PhJ MGP_PWKPhJ_G0027573
 protein coding gene Chr4:115107095-115110670 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027399
 protein coding gene Chr4:117673246-117676688 (-)
WSB/EiJ MGP_WSBEiJ_G0027930
 protein coding gene Chr4:121266723-121270298 (-)



Homology
more
  • Human Ortholog
    TMCO2, transmembrane and coiled-coil domains 2
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TMCO2, transmembrane and coiled-coil domains 2
  • Synonyms
    dJ39G22.2
  • Links
    NCBI Gene ID: 127391
    neXtProt AC: NX_Q7Z6W1
    UniProt: Q7Z6W1

  • Chr Location
    1p34.2; chr1:40245947-40251684 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    1
  • GO References
    1
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 69469 NCBI Gene Model | MGI Sequence Detail 3567 C57BL/6J ±  kb
    transcript NM_001081312 RefSeq | MGI Sequence Detail 710 C57BL/6  
    polypeptide P0C1V4 UniProt | EBI | MGI Sequence Detail 183 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      2 Sequences
    • Protein Ontology
      PR:000032341 transmembrane and coiled-coil domain-containing protein 2
      (term hierarchy)
    • InterPro Domains
      IPR031697 Transmembrane and coiled-coil domain-containing protein 2
    Molecular
    Reagents
    less
    • All nucleic 1
      cDNA 1

      Microarray probesets 3
    References
    more
    • Summaries
      All 29
      Gene Ontology 1
      Phenotypes 13
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory