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Tsr2 Gene Detail
Summary
  • Symbol
    Tsr2
  • Name
    TSR2 20S rRNA accumulation
  • Synonyms
    2310007F12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916749
    NCBI Gene: 69499
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:149870090-149879539 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome X, 68.46 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    218 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916749
 protein coding gene ChrX:149870090-149879539 (-)
129S1/SvImJ MGP_129S1SvImJ_G0036175
 protein coding gene ChrX:148819094-148828475 (-)
A/J MGP_AJ_G0036151
 protein coding gene ChrX:148029372-148038782 (-)
AKR/J MGP_AKRJ_G0036077
 protein coding gene ChrX:152813989-152823438 (-)
BALB/cJ MGP_BALBcJ_G0036142
 protein coding gene ChrX:146220741-146231475 (-)
C3H/HeJ MGP_C3HHeJ_G0035850
 protein coding gene ChrX:149027742-149041878 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036667
 protein coding gene ChrX:153031573-153041386 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0033491
 protein coding gene ChrX:139792358-139800477 (-)
CAST/EiJ MGP_CASTEiJ_G0035141
 protein coding gene ChrX:128467689-128478243 (-)
CBA/J MGP_CBAJ_G0035827
 protein coding gene ChrX:157575183-157586131 (-)
DBA/2J MGP_DBA2J_G0035985
 protein coding gene ChrX:147113452-147122894 (-)
FVB/NJ MGP_FVBNJ_G0035919
 protein coding gene ChrX:146254100-146263922 (-)
LP/J MGP_LPJ_G0036076
 protein coding gene ChrX:149901427-149910873 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035955
 protein coding gene ChrX:165665593-165675540 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036702
 protein coding gene ChrX:148323756-148333218 (-)
PWK/PhJ MGP_PWKPhJ_G0034835
 protein coding gene ChrX:125437203-125446969 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034661
 protein coding gene ChrX:128924238-128935271 (-)
WSB/EiJ MGP_WSBEiJ_G0035276
 protein coding gene ChrX:146426095-146436603 (-)



Homology
more
  • Human Ortholog
    TSR2, TSR2 ribosome maturation factor
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TSR2, TSR2 ribosome maturation factor
  • Synonyms
    DBA14, DT1P1A10, WGG1
  • Links
    NCBI Gene ID: 90121
    neXtProt AC: NX_Q969E8
    UniProt: Q969E8

  • Chr Location
    Xp11.22; chrX:54440404-54448032 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with human TSR2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    3
  • GO References
    2
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    13
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 69499 NCBI Gene Model | MGI Sequence Detail 9450 C57BL/6J ±  kb
transcript NM_001164578 RefSeq | MGI Sequence Detail 3814 C57BL/6  
polypeptide Q8C8T8 UniProt | EBI | MGI Sequence Detail 191 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    cDNA 13

    Microarray probesets 4
References
more
  • Summaries
    All 25
    Gene Ontology 2
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory