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Cdk13 Gene Detail
Summary
  • Symbol
    Cdk13
  • Name
    cyclin dependent kinase 13
  • Synonyms
    2310015O17Rik, Cdc2l5
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916812
    NCBI Gene: 69562
  • Alliance
    gene page
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:17885309-17979960 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 6.05 cM, cytoband A3.1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1648 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916812
 protein coding gene Chr13:17884900-17979960 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020252
 protein coding gene Chr13:14771419-14867417 (-)
A/J MGP_AJ_G0020209
 protein coding gene Chr13:14591497-14685341 (-)
AKR/J MGP_AKRJ_G0020183
 protein coding gene Chr13:14802132-14887049 (-)
BALB/cJ MGP_BALBcJ_G0020195
 protein coding gene Chr13:14551939-14647585 (-)
C3H/HeJ MGP_C3HHeJ_G0019999
 protein coding gene Chr13:14884409-14985847 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020639
 protein coding gene Chr13:15494164-15592102 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018246
 protein coding gene Chr13:13117041-13206989 (-)
CAST/EiJ MGP_CASTEiJ_G0019533
 protein coding gene Chr13:14588789-14689335 (-)
CBA/J MGP_CBAJ_G0019963
 protein coding gene Chr13:15963369-16060105 (-)
DBA/2J MGP_DBA2J_G0020082
 protein coding gene Chr13:14206487-14304420 (-)
FVB/NJ MGP_FVBNJ_G0020063
 protein coding gene Chr13:13910932-14002105 (-)
LP/J MGP_LPJ_G0020152
 protein coding gene Chr13:15051168-15148841 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020101
 protein coding gene Chr13:16316869-16433071 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020667
 protein coding gene Chr13:14598985-14691517 (-)
PWK/PhJ MGP_PWKPhJ_G0019296
 protein coding gene Chr13:14264102-14349300 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019102
 protein coding gene Chr13:13740599-13830203 (-)
WSB/EiJ MGP_WSBEiJ_G0019593
 protein coding gene Chr13:14624449-14716160 (-)



Homology
more
  • Human Ortholog
    CDK13, cyclin dependent kinase 13
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CDK13, cyclin dependent kinase 13
  • Synonyms
    CDC2L, CDC2L5, CHDFIDD, CHED, hCDK13
  • Links
    NCBI Gene ID: 8621
    neXtProt AC: NX_Q14004
    UniProt: Q14004

  • Chr Location
    7p14.1; chr7:39950121-40099580 (+)  GRCh38
Human Diseases
more
  • Diseases
    1 with Cdk13 mouse models; 4 with human CDK13 associations

Human Disease Mouse Models
      
IDs
 View 1 model
      
IDs
IDs
IDs
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    33 phenotypes from 3 alleles in 4 genetic backgrounds
    18 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    39
  • GO References
    12
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    764
  • Tissues
    35
  • cDNA Data
    14
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 69562 NCBI Gene Model | MGI Sequence Detail 94652 C57BL/6J ±  kb
    transcript NM_001081058 RefSeq | MGI Sequence Detail 7081 Not Specified  
    polypeptide Q69ZA1 UniProt | EBI | MGI Sequence Detail 1511 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 15
      cDNA 14
      Other 1

      Microarray probesets 5
    References
    more
    • Summaries
      All 52
      Developmental Gene Expression 3
      Diseases 1
      Gene Ontology 12
      Phenotypes 18
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:350438 Hampl M, et al., Early embryogenesis in CHDFIDD mouse model reveals facial clefts and altered cranial neurogenesis. Dis Model Mech. 2024 Jun 1;17(6)
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory