Slc7a6os MGI Mouse Gene Detail - MGI:1916951 - solute carrier family 7, member 6 opposite strand

Symbol

Slc7a6os
Name

solute carrier family 7, member 6 opposite strand
Synonyms

2010007L18Rik, 2400002F02Rik

Feature Type

protein coding gene
IDs

MGI:1916951
NCBI Gene: 66432
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr8:106927349-106937567 bp, - strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 8, 53.11 cM
Mapping Data

2 experiments

SNPs within 2kb

304 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1916951	protein coding gene	Chr8:106927070-106937567 (-)
129S1/SvImJ	MGP_129S1SvImJ_G0034079	protein coding gene	Chr8:108553224-108564871 (-)
A/J	MGP_AJ_G0034060	protein coding gene	Chr8:104210167-104220970 (-)
AKR/J	MGP_AKRJ_G0033986	protein coding gene	Chr8:107228425-107240927 (-)
BALB/cJ	MGP_BALBcJ_G0034053	protein coding gene	Chr8:104391847-104402704 (-)
C3H/HeJ	MGP_C3HHeJ_G0033765	protein coding gene	Chr8:107957652-107970284 (-)
C57BL/6NJ	MGP_C57BL6NJ_G0034573	protein coding gene	Chr8:112527111-112539917 (-)
CAROLI/EiJ	MGP_CAROLIEiJ_G0031515	protein coding gene	Chr8:97340395-97349402 (-)
CAST/EiJ	MGP_CASTEiJ_G0033091	protein coding gene	Chr8:107484696-107497159 (-)
CBA/J	MGP_CBAJ_G0033738	protein coding gene	Chr8:116146159-116156497 (-)
DBA/2J	MGP_DBA2J_G0033893	protein coding gene	Chr8:103544559-103555098 (-)
FVB/NJ	MGP_FVBNJ_G0033838	protein coding gene	Chr8:102478032-102489015 (-)
LP/J	MGP_LPJ_G0033984	protein coding gene	Chr8:108758571-108770984 (-)
NOD/ShiLtJ	MGP_NODShiLtJ_G0033882	protein coding gene	Chr8:119329606-119340803 (-)
NZO/HlLtJ	MGP_NZOHlLtJ_G0034591	protein coding gene	Chr8:107187046-107199083 (-)
PWK/PhJ	MGP_PWKPhJ_G0032792	protein coding gene	Chr8:102963548-102973977 (-)
SPRET/EiJ	MGP_SPRETEiJ_G0032633	protein coding gene	Chr8:105892068-105902670 (-)
WSB/EiJ	MGP_WSBEiJ_G0033207	protein coding gene	Chr8:107875109-107886485 (-)

Human Ortholog

SLC7A6OS, solute carrier family 7 member 6 opposite strand

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SLC7A6OS, solute carrier family 7 member 6 opposite strand
Synonyms

EPM12, Iwr1
Links

HGNC:25807

NCBI Gene ID: 84138

neXtProt AC: NX_Q96CW6

UniProt: Q96CW6
Chr Location

16q22.1; chr16:68284503-68310946 (-) GRCh38

MGI Vertebrate Homology

Slc7a6os stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: SLC7A6OS
Gene Tree

Slc7a6os

Diseases

1 with human SLC7A6OS associations

				Human Disease	Mouse Models
				progressive myoclonus epilepsy IDs progressive myoclonus epilepsy DOID:891 MESH:D020191 NCI:C7636 OMIM:310370 OMIM:PS254800 UMLS_CUI:C0751778

Click on a disease name to see all genes associated with that disease.

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Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
9 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

9
Endonuclease-mediated

3
Gene trapped

4
Targeted

2
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

23 strains or lines available

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All GO Annotations

5
GO References

4

Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

752
Tissues

11
cDNA Data

36
Literature Summary

2

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase slc7a6os

ZFIN slc7a6os

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All Sequences

41
RefSeq

3
UniProt

1
CCDS

CCDS22632.1

Ensembl

ENSMUSG00000033106 (Evidence)
NCBI Gene

66432

			Length	Strain/Species	Flank
genomic	ENSMUSG00000033106	Ensembl Gene Model \| MGI Sequence Detail	10219	C57BL/6J	± kb
transcript	ENSMUST00000035925	Ensembl \| MGI Sequence Detail	1246	Not Applicable
polypeptide	ENSMUSP00000039029	Ensembl \| MGI Sequence Detail	306	Not Applicable

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UniProt

1 Sequence
Protein Ontology

PR:000015203 protein SLC7A6OS

(term hierarchy)
InterPro Domains

IPR040218 Probable RNA polymerase II nuclear localization protein SLC7A6OS

IPR013883 Transcription factor Iwr1 domain

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All nucleic 38

cDNA 36

Primer pair 2

Microarray probesets 3

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MGI:1913682

Summaries

All 35

Developmental Gene Expression 2

Gene Ontology 4

Phenotypes 9
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Slc7a6os:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr82760	Chr8:106937556-106937574 (-)	2 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24