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Iqcg Gene Detail
Summary
  • Symbol
    Iqcg
  • Name
    IQ motif containing G
  • Synonyms
    2400003L07Rik, esgd12d, G1-374-12, repro1, stubby12d
  • Feature Type
    protein coding gene
  • IDs
    MGI:1916957
    NCBI Gene: 69707
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:32834640-32876617 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 23.55 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1217 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1916957
 protein coding gene Chr16:32833053-32876617 (-)
129S1/SvImJ MGP_129S1SvImJ_G0022750
 protein coding gene Chr16:31152411-31210244 (-)
A/J MGP_AJ_G0022715
 protein coding gene Chr16:29680188-29726328 (-)
AKR/J MGP_AKRJ_G0022688
 protein coding gene Chr16:30725109-30771421 (-)
BALB/cJ MGP_BALBcJ_G0022717
 protein coding gene Chr16:29798795-29838523 (-)
C3H/HeJ MGP_C3HHeJ_G0022482
 protein coding gene Chr16:30851201-30899717 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023166
 protein coding gene Chr16:31827164-31911879 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0020684
 protein coding gene Chr16:30035626-30070466 (-)
CAST/EiJ MGP_CASTEiJ_G0022010
 protein coding gene Chr16:30999129-31046207 (-)
CBA/J MGP_CBAJ_G0022452
 protein coding gene Chr16:33103571-33156313 (-)
DBA/2J MGP_DBA2J_G0022585
 protein coding gene Chr16:29504597-29546864 (-)
FVB/NJ MGP_FVBNJ_G0022560
 protein coding gene Chr16:29495388-29539943 (-)
LP/J MGP_LPJ_G0022652
 protein coding gene Chr16:30918383-30964820 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0022579
 protein coding gene Chr16:32508978-32586026 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023178
 protein coding gene Chr16:30731267-30776585 (-)
PWK/PhJ MGP_PWKPhJ_G0021751
 protein coding gene Chr16:29845115-29899276 (-)
SPRET/EiJ MGP_SPRETEiJ_G0021580
 protein coding gene Chr16:30527587-30575589 (-)
WSB/EiJ MGP_WSBEiJ_G0022054
 protein coding gene Chr16:30699170-30747749 (-)



Homology
more
  • Human Ortholog
    IQCG, IQ motif containing G
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IQCG, IQ motif containing G
  • Synonyms
    CFAP122, DRC9
  • Links
    NCBI Gene ID: 84223
    neXtProt AC: NX_Q9H095
    UniProt: Q9H095

  • Chr Location
    3q29; chr3:197889077-197960177 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    19 phenotypes from 3 alleles in 5 genetic backgrounds
    7 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Homozygous male mice are infertile and have very low epididymal sperm concentration with low motility, predominantly appearing as sperm heads without tails or with short tails.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    779
  • Tissues
    14
  • cDNA Data
    6
  • Literature Summary
    2
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 69707 NCBI Gene Model | MGI Sequence Detail 41978 C57BL/6J ±  kb
    transcript NM_178378 RefSeq | MGI Sequence Detail 4027 Not Specified  
    polypeptide Q80W32 UniProt | EBI | MGI Sequence Detail 419 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 6
      cDNA 6

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:3050605
    References
    more
    • Summaries
      All 28
      Developmental Gene Expression 2
      Gene Ontology 6
      Phenotypes 7
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:240319 Stauber M, et al., Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory