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Pik3ip1 Gene Detail
Summary
  • Symbol
    Pik3ip1
  • Name
    phosphoinositide-3-kinase interacting protein 1
  • Synonyms
    1500004A08Rik, 5830455E04Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917016
    NCBI Gene: 216505
  • Alliance
    gene page
  • Transcription Start Sites
    15 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:3280731-3292971 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 2.33 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    340 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917016
 protein coding gene Chr11:3280401-3292971 (+)
129S1/SvImJ MGP_129S1SvImJ_G0017955
 protein coding gene Chr11:182019-195322 (+)
A/J MGP_AJ_G0017928
 protein coding gene Chr11:244032-256617 (+)
AKR/J MGP_AKRJ_G0017892
 protein coding gene Chr11:251389-265207 (+)
BALB/cJ MGP_BALBcJ_G0017896
 protein coding gene Chr11:216098-228640 (+)
C3H/HeJ MGP_C3HHeJ_G0017709
 protein coding gene Chr11:191916-206421 (+)
C57BL/6NJ MGP_C57BL6NJ_G0018349
 protein coding gene Chr11:250118-264346 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016008
 protein coding gene Chr11:160809-173595 (+)
CAST/EiJ MGP_CASTEiJ_G0017271
 protein coding gene Chr11:140992-155193 (+)
CBA/J MGP_CBAJ_G0017684
 protein coding gene Chr11:416415-428951 (+)
DBA/2J MGP_DBA2J_G0017795
 protein coding gene Chr11:165478-178011 (+)
FVB/NJ MGP_FVBNJ_G0017786
 protein coding gene Chr11:191378-204946 (+)
LP/J MGP_LPJ_G0017865
 protein coding gene Chr11:288818-301395 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0017812
 protein coding gene Chr11:172220-184779 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0018388
 protein coding gene Chr11:257886-270394 (+)
PWK/PhJ MGP_PWKPhJ_G0017051
 protein coding gene Chr11:140224-153289 (+)
SPRET/EiJ MGP_SPRETEiJ_G0016847
 protein coding gene Chr11:219246-231748 (+)
WSB/EiJ MGP_WSBEiJ_G0017325
 protein coding gene Chr11:136334-150254 (+)



Homology
more
  • Human Ortholog
    PIK3IP1, phosphoinositide-3-kinase interacting protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    PIK3IP1, phosphoinositide-3-kinase interacting protein 1
  • Synonyms
    HGFL, hHGFL(S), TrIP
  • Links
    NCBI Gene ID: 113791
    neXtProt AC: NX_Q96FE7
    UniProt: Q96FE7

  • Chr Location
    22q12.2; chr22:31281593-31292534 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    13 phenotype references
Mice homozygous for an ENU-induced allele exhibit normal blood lymphocyte populations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    9
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    813
  • Tissues
    24
  • cDNA Data
    15
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 216505 NCBI Gene Model | MGI Sequence Detail 12241 C57BL/6J ±  kb
transcript NM_178149 RefSeq | MGI Sequence Detail 2267 C57BL/6  
polypeptide Q7TMJ8 UniProt | EBI | MGI Sequence Detail 264 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 16
    cDNA 15
    Primer pair 1

    Microarray probesets 7
Other
Accession IDs
less
MGI:1923333
References
more
  • Summaries
    All 42
    Developmental Gene Expression 3
    Gene Ontology 5
    Phenotypes 13
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:329897 Xie W, et al., Regulation of autoimmune disease progression by Pik3ip1 through metabolic reprogramming in T cells and therapeutic implications. Sci Adv. 2022 Sep 30;8(39):eabo4250
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory