Krtcap3 Gene Detail

Summary

• Symbol
  Krtcap3
• Name
  keratinocyte associated protein 3
• Synonyms
  2010001C09Rik

• Feature Type
  protein coding gene
• IDs
  MGI:1917065
  NCBI Gene: 69815
• Alliance
  gene page
• Transcription Start Sites
  3 TSS

Location &
Maps

• Sequence Map
  Chr5:31409050-31410541 bp, + strand

  From NCBI annotation of GRCm39
  

• View this region in JBrowse
  

• Genome Browsers
  Ensembl | UCSC | NCBI

• Genetic Map
  Chromosome 5, 17.27 cM
• Mapping Data
  2 experiments

Strain
Comparison

• SNPs within 2kb
  85 from dbSNP Build 142
• Strain Annotations
  18

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1917065	protein coding gene	Chr5:31409035-31410546 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0029421	protein coding gene	Chr5:29244231-29245742 (+)
A/J	MGP_AJ_G0029387	protein coding gene	Chr5:28282720-28284231 (+)
AKR/J	MGP_AKRJ_G0029337	protein coding gene	Chr5:29433229-29434742 (+)
BALB/cJ	MGP_BALBcJ_G0029398	protein coding gene	Chr5:28797442-28798953 (+)
C3H/HeJ	MGP_C3HHeJ_G0029119	protein coding gene	Chr5:29454406-29455917 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0029851	protein coding gene	Chr5:31058479-31059990 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0027089	protein coding gene	Chr5:25748370-25749884 (+)
CAST/EiJ	MGP_CASTEiJ_G0028529	protein coding gene	Chr5:28536667-28538180 (+)
CBA/J	MGP_CBAJ_G0029087	protein coding gene	Chr5:31629177-31630688 (+)
DBA/2J	MGP_DBA2J_G0029236	protein coding gene	Chr5:28459340-28460851 (+)
FVB/NJ	MGP_FVBNJ_G0029194	protein coding gene	Chr5:27878439-27879950 (+)
LP/J	MGP_LPJ_G0029321	protein coding gene	Chr5:29697843-29699354 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0029223	protein coding gene	Chr5:32493035-32494546 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0029885	protein coding gene	Chr5:28948853-28950364 (+)
PWK/PhJ	MGP_PWKPhJ_G0028254	protein coding gene	Chr5:27583368-27584879 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0028085	protein coding gene	Chr5:28342917-28344428 (+)
WSB/EiJ	MGP_WSBEiJ_G0028610	protein coding gene	Chr5:29012770-29014281 (+)

Homology

• Human Ortholog
  KRTCAP3, keratinocyte associated protein 3

• Vertebrate Orthologs
  2

Vertebrate Orthology Source

Alliance of Genome Resources

• Human Ortholog
  KRTCAP3, keratinocyte associated protein 3
  
• Synonyms
  KCP3
• Links
  HGNC:28943

  NCBI Gene ID: 200634

  neXtProt AC: NX_Q53RY4

  UniProt: Q53RY4

  
  
• Chr Location
  2p23.3; chr2:27442366-27446481 (+)  GRCh38

---

• MGI Vertebrate Homology
  Krtcap3 stringent orthology
  1 human;1 mouse;1 rat
  
• HCOP
  vertebrate homology predictions: KRTCAP3
• Gene Tree
  Krtcap3
  

Human Diseases

• References
  1 with disease annotations

Mutations,
Alleles, and
Phenotypes

• Phenotype Summary
  22 phenotype references
  

• All Mutations and Alleles
  6
• Chemically induced (other)
  2
• Radiation induced
  2
• Spontaneous
  1
• Targeted
  1
• Genomic Mutations
  5 involving Krtcap3
• Incidental Mutations
  Mutagenetix , APF
• Find Mice (IMSR)
  8 strains or lines available

Gene Ontology
(GO)
Classifications

• All GO Annotations
  1
• GO References
  1

Expression

• Assay Results
  706
• cDNA Data
  26

Tissue x Stage Matrix

• Other Mouse Links
  Allen Institute
  GEO
  Expression Atlas
• Other Vertebrate Links
  Xenbase krtcap3

Sequences &
Gene Models

• All Sequences
  48
• RefSeq
  4
• UniProt
  2
• CCDS
  CCDS51459.1

• Ensembl
  ENSMUSG00000029149 (Evidence)
• NCBI Gene
  69815

Representative Sequences			Length	Strain/Species
genomic	69815	NCBI Gene Model | MGI Sequence Detail	1492	C57BL/6J
transcript	NM_027221	RefSeq | MGI Sequence Detail	922	C57BL/6
polypeptide	Q8K177	UniProt | EBI | MGI Sequence Detail	240	Not Applicable

Protein
Information

• UniProt
  2 Sequences
• Protein Ontology
  PR:000009589 keratinocyte-associated protein 3
  (term hierarchy)
• InterPro Domains
  IPR020977 Beta-casein-like

Molecular
Reagents

• All nucleic 26

  cDNA 26

  
  

  Microarray probesets 4

Other
Accession IDs

MGI:2141187

References

• Summaries
  All 42

  Diseases 1

  Gene Ontology 1

  Phenotypes 22
• Earliest
  J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
• Latest
  J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

TSS for Krtcap3:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr45697	Chr5:31409022-31409072 (+)	-3 bp
Tssr45698	Chr5:31409087-31409102 (+)	45 bp
Tssr45699	Chr5:31409255-31409266 (+)	211 bp