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Nt5m Gene Detail
Summary
  • Symbol
    Nt5m
  • Name
    5',3'-nucleotidase, mitochondrial
  • Synonyms
    2010013E09Rik, dNT-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917127
    NCBI Gene: 103850
  • Alliance
    genome feature page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:59730233-59767359 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 37.80 cM, cytoband B
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    933 from dbSNP Build 142
  • Strain Annotations
    15
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917127
 protein coding gene Chr11:59730233-59771794 (+)
129S1/SvImJ ENSMUSG00200036223
 protein coding gene Chr11:56746030-56776674 (+)
A/J ENSMUSG00195035718
 protein coding gene Chr11:56682989-56713756 (+)
AKR/J no annotation
BALB/cJ ENSMUSG00180048804
 protein coding gene Chr11:56762157-56792815 (+)
C3H/HeJ ENSMUSG00175042876
 protein coding gene Chr11:56718112-56748878 (+)
C57BL/6NJ ENSMUSG00215021928
 protein coding gene Chr11:56529472-56560125 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0016446
 protein coding gene Chr11:54663098-54705146 (+)
CAST/EiJ no annotation
CBA/J ENSMUSG00210034437
 protein coding gene Chr11:56569471-56600234 (+)
DBA/2J ENSMUSG00185037669
 protein coding gene Chr11:56745751-56776401 (+)
FVB/NJ ENSMUSG00205039311
 protein coding gene Chr11:56635883-56666490 (+)
JF1/MsJ ENSUMUG00000011583
 protein coding gene Chr11:57101436-57132221 (+)
LP/J ENSMUSG00230046871
 protein coding gene Chr11:57954019-57984659 (+)
NOD/ShiLtJ no annotation
NZO/HlLtJ ENSMUSG00225032332
 protein coding gene Chr11:59966095-59996719 (+)
PWK/PhJ ENSLUMG00010025804
 protein coding gene Chr11:56562296-56592935 (+)
SPRET/EiJ ENSMSPG00010039515
 protein coding gene Chr11:57339736-57370649 (+)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    NT5M, 5',3'-nucleotidase, mitochondrial
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    NT5M, 5',3'-nucleotidase, mitochondrial
  • Synonyms
    dNT-2, dNT2, mdN
  • Links
    NCBI Gene ID: 56953
    UniProt: Q9NPB1

  • Chr Location
    17p11.2; chr17:17303331-17347663 (+)  GRCh38
Human Diseases
less
  • References
    3 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    21 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    36
  • GO References
    11
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    720
  • Tissues
    98
  • cDNA Data
    50
  • Literature Summary
    2
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 103850 NCBI Gene Model | MGI Sequence Detail 37127 C57BL/6J ±  kb
transcript NM_001418354 RefSeq | MGI Sequence Detail 1428 C57BL/6  
polypeptide Q8VCE6 UniProt | EBI | MGI Sequence Detail 220 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 51
    Genomic 1
    cDNA 50

    Microarray probesets 3
Other
Accession IDs
less
MGI:2144290
References
more
  • Summaries
    All 52
    Developmental Gene Expression 2
    Diseases 3
    Gene Ontology 11
    Phenotypes 21
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:185284 Lacaria M, et al., Enriched rearing improves behavioral responses of an animal model for CNV-based autistic-like traits. Hum Mol Genet. 2012 Jul 15;21(14):3083-96
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory