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Mrto4 Gene Detail
Summary
  • Symbol
    Mrto4
  • Name
    mRNA turnover 4, ribosome maturation factor
  • Synonyms
    2610012O22Rik, Mrt4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917152
    NCBI Gene: 69902
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:139074751-139079887 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 4, 70.65 cM, cytoband D3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    242 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917152
 protein coding gene Chr4:139074746-139079887 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029016
 protein coding gene Chr4:142179884-142184713 (-)
A/J MGP_AJ_G0028975
 protein coding gene Chr4:136064715-136071308 (-)
AKR/J MGP_AKRJ_G0028927
 protein coding gene Chr4:139964833-139970006 (-)
BALB/cJ MGP_BALBcJ_G0028999
 protein coding gene Chr4:136738042-136743204 (-)
C3H/HeJ MGP_C3HHeJ_G0028713
 protein coding gene Chr4:140342878-140348405 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029440
 protein coding gene Chr4:147211031-147216172 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026711
 protein coding gene Chr4:129021166-129026434 (-)
CAST/EiJ MGP_CASTEiJ_G0028145
 protein coding gene Chr4:138527987-138533114 (-)
CBA/J MGP_CBAJ_G0028677
 protein coding gene Chr4:151459900-151470073 (-)
DBA/2J MGP_DBA2J_G0028827
 protein coding gene Chr4:136460444-136465606 (-)
FVB/NJ MGP_FVBNJ_G0028794
 protein coding gene Chr4:135488052-135493390 (-)
LP/J MGP_LPJ_G0028926
 protein coding gene Chr4:142251701-142258502 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028820
 protein coding gene Chr4:155367697-155372814 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029478
 protein coding gene Chr4:140491273-140498824 (-)
PWK/PhJ MGP_PWKPhJ_G0027866
 protein coding gene Chr4:133309608-133315316 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027691
 protein coding gene Chr4:136270389-136275503 (-)
WSB/EiJ MGP_WSBEiJ_G0028223
 protein coding gene Chr4:140746360-140751504 (-)



Homology
more
  • Human Ortholog
    MRTO4, MRT4 homolog, ribosome maturation factor
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MRTO4, MRT4 homolog, ribosome maturation factor
  • Synonyms
    C1orf33, dJ657E11.4, MRT4
  • Links
    NCBI Gene ID: 51154
    neXtProt AC: NX_Q9UKD2
    UniProt: Q9UKD2

  • Chr Location
    1p36.13; chr1:19251805-19260128 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    11 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    756
  • Tissues
    16
  • cDNA Data
    7
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 69902 NCBI Gene Model | MGI Sequence Detail 5137 C57BL/6J ±  kb
transcript NM_001356476 RefSeq | MGI Sequence Detail 1264 C57BL/6  
polypeptide Q9D0I8 UniProt | EBI | MGI Sequence Detail 239 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000010649 mRNA turnover protein 4
    (term hierarchy)
  • InterPro Domains
    IPR001790 Large ribosomal subunit protein uL10
    IPR043141 Large ribosomal subunit protein uL10-like domain superfamily
    IPR040637 Large ribosomal subunit protein uL10-like, insertion domain
    IPR043164 Large ribosomal subunit protein uL10-like, insertion domain superfamily
    IPR051742 Ribosomal Assembly Factor uL10
    IPR033867 Ribosome assembly factor Mrt4
Molecular
Reagents
less
  • All nucleic 7
    cDNA 7

    Microarray probesets 5
References
more
  • Summaries
    All 34
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:326541 Cyagen Biosciences Inc., Cyagen Biosciences Website. 2022;
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory