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Ogfrl1 Gene Detail
Summary
  • Symbol
    Ogfrl1
  • Name
    opioid growth factor receptor-like 1
  • Synonyms
    2210417C17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917405
    NCBI Gene: 70155
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:23405505-23422282 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 1, 9.57 cM, cytoband A5
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    602 from dbSNP Build 142
  • Strain Annotations
    12
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917405
protein coding gene Chr1:23405505-23436853 (-)
129S1/SvImJ no annotation
A/J MGP_AJ_G0015865
protein coding gene Chr1:20758653-20792907 (-)
AKR/J MGP_AKRJ_G0015822
protein coding gene Chr1:20921546-20955038 (-)
BALB/cJ no annotation
C3H/HeJ MGP_C3HHeJ_G0015655
protein coding gene Chr1:20946116-20980040 (-)
C57BL/6NJ no annotation
CAROLI/EiJ MGP_CAROLIEiJ_G0013994
protein coding gene Chr1:18882201-18909689 (-)
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0015627
protein coding gene Chr1:22657706-22693708 (-)
DBA/2J MGP_DBA2J_G0015726
protein coding gene Chr1:20260688-20291655 (-)
FVB/NJ MGP_FVBNJ_G0015730
protein coding gene Chr1:20036867-20068089 (-)
LP/J MGP_LPJ_G0015798
protein coding gene Chr1:21344025-21392371 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0015750
protein coding gene Chr1:23654045-23687450 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016322
protein coding gene Chr1:20884631-20918808 (-)
PWK/PhJ no annotation
SPRET/EiJ MGP_SPRETEiJ_G0014798
protein coding gene Chr1:20980554-21009641 (-)
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    OGFRL1, opioid growth factor receptor like 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    OGFRL1, opioid growth factor receptor like 1
  • Synonyms
    dJ331H24.1
  • Links
    NCBI Gene ID: 79627
    neXtProt AC: NX_Q5TC84
    UniProt: Q5TC84

  • Chr Location
    6q13

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 70155 NCBI Gene Model | MGI Sequence Detail 16778 C57BL/6J ±  kb
transcript NM_001379082 RefSeq | MGI Sequence Detail 4861 C57BL/6  
polypeptide Q8VE52 UniProt | EBI | MGI Sequence Detail 464 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • Protein Ontology
    PR:000011615 opioid growth factor receptor-like protein 1
  • InterPro Domains
    IPR039574 Opioid growth factor receptor
    IPR006757 Opioid growth factor receptor (OGFr) conserved domain
  • GlyGen
    Q8VE52 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 144
    cDNA 143
    Primer pair 1

    Microarray probesets 9
References
more
  • Summaries
    All 30
    Developmental Gene Expression 4
    Gene Ontology 1
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:313619 Bedogni F, et al., Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
11/05/2024
MGI 6.24
The Jackson Laboratory