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Srp68 Gene Detail
Summary
  • Symbol
    Srp68
  • Name
    signal recognition particle 68
  • Synonyms
    2610024I03Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917447
    NCBI Gene: 217337
  • Alliance
    gene page
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:116135992-116165043 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 81.06 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    969 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917447
 protein coding gene Chr11:116135992-116165043 (-)
129S1/SvImJ MGP_129S1SvImJ_G0019421
 protein coding gene Chr11:120343068-120372111 (-)
A/J MGP_AJ_G0019390
 protein coding gene Chr11:115086789-115116487 (-)
AKR/J MGP_AKRJ_G0019360
 protein coding gene Chr11:118516497-118545744 (-)
BALB/cJ MGP_BALBcJ_G0019364
 protein coding gene Chr11:115497086-115526112 (-)
C3H/HeJ MGP_C3HHeJ_G0019170
 protein coding gene Chr11:118867864-118896899 (-)
C57BL/6NJ MGP_C57BL6NJ_G0019814
 protein coding gene Chr11:124032423-124065760 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0017437
 protein coding gene Chr11:112096212-112126862 (-)
CAST/EiJ MGP_CASTEiJ_G0018725
 protein coding gene Chr11:120227278-120256419 (-)
CBA/J MGP_CBAJ_G0019142
 protein coding gene Chr11:128924924-128956889 (-)
DBA/2J MGP_DBA2J_G0019253
 protein coding gene Chr11:114501652-114530705 (-)
FVB/NJ MGP_FVBNJ_G0019245
 protein coding gene Chr11:114017281-114048060 (-)
LP/J MGP_LPJ_G0019323
 protein coding gene Chr11:120726798-120755841 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0019278
 protein coding gene Chr11:128006092-128035205 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0019852
 protein coding gene Chr11:119174393-119204265 (-)
PWK/PhJ MGP_PWKPhJ_G0018489
 protein coding gene Chr11:115836106-115865378 (-)
SPRET/EiJ MGP_SPRETEiJ_G0018282
 protein coding gene Chr11:118925164-118957366 (-)
WSB/EiJ MGP_WSBEiJ_G0018777
 protein coding gene Chr11:119142194-119172414 (-)



Homology
more
  • Human Ortholog
    SRP68, signal recognition particle 68
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SRP68, signal recognition particle 68
  • Synonyms
    SCN10
  • Links
    NCBI Gene ID: 6730
    neXtProt AC: NX_Q9UHB9
    UniProt: Q9UHB9

  • Chr Location
    17q25.1; chr17:76038775-76072517 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with human SRP68 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    24
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    167
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 217337 NCBI Gene Model | MGI Sequence Detail 29052 C57BL/6J ±  kb
transcript NM_146032 RefSeq | MGI Sequence Detail 2546 C57BL/6  
polypeptide Q8BMA6 UniProt | EBI | MGI Sequence Detail 625 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000015626 signal recognition particle subunit SRP68
    (term hierarchy)
  • InterPro Domains
    IPR026258 Signal recognition particle subunit SRP68
    IPR034652 Signal recognition particle subunit SRP68, RNA-binding domain
    IPR038253 SRP68, N-terminal domain superfamily
  • GlyGen
    Q8BMA6 1 site, 1 O-linked glycan (1 site)
Molecular
Reagents
less
  • All nucleic 167
    cDNA 167

    Microarray probesets 4
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:343072 Vermeiren S, et al., Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia. iScience. 2023 Dec 15;26(12):108364
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory