About   Help   FAQ
Gtf3c5 Gene Detail
Summary
  • Symbol
    Gtf3c5
  • Name
    general transcription factor IIIC, polypeptide 5
  • Synonyms
    2700084A09Rik, TFiiiC2-63, TFIIIC63, TFIIICepsilon
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917489
    NCBI Gene: 70239
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:28456257-28473291 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 2, 19.38 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    495 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917489
 protein coding gene Chr2:28456257-28473763 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025527
 protein coding gene Chr2:26631751-26651581 (-)
A/J MGP_AJ_G0025504
 protein coding gene Chr2:25619227-25637548 (-)
AKR/J MGP_AKRJ_G0025474
 protein coding gene Chr2:26467610-26484924 (-)
BALB/cJ MGP_BALBcJ_G0025500
 protein coding gene Chr2:25740234-25757400 (-)
C3H/HeJ MGP_C3HHeJ_G0025261
 protein coding gene Chr2:26393131-26411797 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025944
 protein coding gene Chr2:27527098-27544115 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023354
 protein coding gene Chr2:24431861-24450976 (-)
CAST/EiJ MGP_CASTEiJ_G0024724
 protein coding gene Chr2:26295392-26314178 (-)
CBA/J MGP_CBAJ_G0025239
 protein coding gene Chr2:28460846-28478754 (-)
DBA/2J MGP_DBA2J_G0025372
 protein coding gene Chr2:25427305-25444999 (-)
FVB/NJ MGP_FVBNJ_G0025334
 protein coding gene Chr2:25213620-25231759 (-)
LP/J MGP_LPJ_G0025458
 protein coding gene Chr2:26583126-26600393 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025365
 protein coding gene Chr2:28464691-28496997 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026003
 protein coding gene Chr2:26381512-26403640 (-)
PWK/PhJ MGP_PWKPhJ_G0024471
 protein coding gene Chr2:25234287-25251986 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024271
 protein coding gene Chr2:26511558-26529647 (-)
WSB/EiJ MGP_WSBEiJ_G0024793
 protein coding gene Chr2:26514525-26533367 (-)



Homology
more
  • Human Ortholog
    GTF3C5, general transcription factor IIIC subunit 5
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    GTF3C5, general transcription factor IIIC subunit 5
  • Synonyms
    TFiiiC2-63, TFIIIC63, TFIIICepsilon
  • Links
    NCBI Gene ID: 9328
    neXtProt AC: NX_Q9Y5Q8
    UniProt: Q9Y5Q8

  • Chr Location
    9q34.13; chr9:133030675-133058503 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    11
  • GO References
    6
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    822
  • Tissues
    109
  • cDNA Data
    69
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 70239 NCBI Gene Model | MGI Sequence Detail 17035 C57BL/6J ±  kb
transcript NM_001290484 RefSeq | MGI Sequence Detail 2823 C57BL/6  
polypeptide Q8R2T8 UniProt | EBI | MGI Sequence Detail 520 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000008329 general transcription factor 3C polypeptide 5
    (term hierarchy)
  • InterPro Domains
    IPR042536 TFIIIC, subcomplex tauA subunit Sfc1, triple barrel domain superfamily
    IPR019136 Transcription factor IIIC subunit 5, HTH domain
    IPR040454 Transcription factor IIIC subunit Tfc1/Sfc1
    IPR041499 Transcription factor IIIC subunit Tfc1/Sfc1, triple barrel domain
Molecular
Reagents
less
  • All nucleic 70
    cDNA 69
    Primer pair 1

    Microarray probesets 3
References
more
  • Summaries
    All 36
    Developmental Gene Expression 3
    Gene Ontology 6
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory