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Spdl1 Gene Detail
Summary
  • Symbol
    Spdl1
  • Name
    spindle apparatus coiled-coil protein 1
  • Synonyms
    1700018I02Rik, 2600001J17Rik, 2810049B11Rik, Ccdc99
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917635
    NCBI Gene: 70385
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr11:34700017-34724468 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 11, 19.90 cM, cytoband A5
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    757 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917635
 protein coding gene Chr11:34700012-34724492 (-)
129S1/SvImJ MGP_129S1SvImJ_G0018153
 protein coding gene Chr11:33163116-33187690 (-)
A/J MGP_AJ_G0018126
 protein coding gene Chr11:31924830-31951546 (-)
AKR/J MGP_AKRJ_G0018090
 protein coding gene Chr11:32889928-32914637 (-)
BALB/cJ MGP_BALBcJ_G0018095
 protein coding gene Chr11:32097782-32123001 (-)
C3H/HeJ MGP_C3HHeJ_G0017908
 protein coding gene Chr11:32843713-32874434 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018549
 protein coding gene Chr11:34205509-34231682 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0016204
 protein coding gene Chr11:30406025-30429816 (-)
CAST/EiJ MGP_CASTEiJ_G0017472
 protein coding gene Chr11:32836721-32862296 (-)
CBA/J MGP_CBAJ_G0017881
 protein coding gene Chr11:35899946-35924160 (-)
DBA/2J MGP_DBA2J_G0017991
 protein coding gene Chr11:31678347-31703180 (-)
FVB/NJ MGP_FVBNJ_G0017985
 protein coding gene Chr11:31513824-31538610 (-)
LP/J MGP_LPJ_G0018063
 protein coding gene Chr11:33416732-33442097 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0018009
 protein coding gene Chr11:36631563-36655825 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018588
 protein coding gene Chr11:32934567-32958903 (-)
PWK/PhJ MGP_PWKPhJ_G0017253
 protein coding gene Chr11:31753660-31778951 (-)
SPRET/EiJ MGP_SPRETEiJ_G0017045
 protein coding gene Chr11:32689029-32713342 (-)
WSB/EiJ MGP_WSBEiJ_G0017521
 protein coding gene Chr11:32692057-32717598 (-)



Homology
more
  • Human Ortholog
    SPDL1, spindle apparatus coiled-coil protein 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SPDL1, spindle apparatus coiled-coil protein 1
  • Synonyms
    CCDC99
  • Links
    NCBI Gene ID: 54908
    neXtProt AC: NX_Q96EA4
    UniProt: Q96EA4

  • Chr Location
    5q35.1; chr5:169583636-169604778 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
  • All Mutations and Alleles
    7
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    2
  • Gene trapped
    2
  • Targeted
    2
  • Genomic Mutations
    1 involving Spdl1
  • Incidental Mutations
    APF , CvDC
  • Find Mice (IMSR)
    34 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    28
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    875
  • Tissues
    23
  • cDNA Data
    45
  • Literature Summary
    4
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000069910 Ensembl Gene Model | MGI Sequence Detail 24452 C57BL/6J ±  kb
transcript ENSMUST00000093191 Ensembl | MGI Sequence Detail 2505 Not Applicable  
polypeptide ENSMUSP00000090882 Ensembl | MGI Sequence Detail 608 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 46
    cDNA 45
    Primer pair 1

    Microarray probesets 2
Other
Accession IDs
less
MGI:1919953, MGI:1923654, MGI:2144000
References
more
  • Summaries
    All 41
    Developmental Gene Expression 4
    Gene Ontology 7
    Phenotypes 8
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:336298 Taliani V, et al., The long noncoding RNA Charme supervises cardiomyocyte maturation by controlling cell differentiation programs in the developing heart. Elife. 2023 Mar 6;12
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory