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Vps26b Gene Detail
Summary
  • Symbol
    Vps26b
  • Name
    VPS26 retromer complex component B
  • Synonyms
    1810012I05Rik, 2310075A12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917656
    NCBI Gene: 69091
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:26919067-26941361 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 9, 12.07 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    635 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917656
 protein coding gene Chr9:26915798-26941390 (-)
129S1/SvImJ MGP_129S1SvImJ_G0034505
 protein coding gene Chr9:24464932-24491988 (-)
A/J MGP_AJ_G0034483
 protein coding gene Chr9:23922729-23949341 (-)
AKR/J MGP_AKRJ_G0034409
 protein coding gene Chr9:24402537-24427994 (-)
BALB/cJ MGP_BALBcJ_G0034474
 protein coding gene Chr9:23807247-23833351 (-)
C3H/HeJ MGP_C3HHeJ_G0034186
 protein coding gene Chr9:24773076-24799856 (-)
C57BL/6NJ MGP_C57BL6NJ_G0034995
 protein coding gene Chr9:25369119-25397719 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0031925
 protein coding gene Chr9:22840659-22865911 (-)
CAST/EiJ MGP_CASTEiJ_G0033509
 protein coding gene Chr9:24570902-24598042 (-)
CBA/J MGP_CBAJ_G0034159
 protein coding gene Chr9:26279733-26305087 (-)
DBA/2J MGP_DBA2J_G0034317
 protein coding gene Chr9:23954014-23979536 (-)
FVB/NJ MGP_FVBNJ_G0034260
 protein coding gene Chr9:23381966-23407893 (-)
LP/J MGP_LPJ_G0034403
 protein coding gene Chr9:24661790-24690259 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0034304
 protein coding gene Chr9:27973974-28000888 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035015
 protein coding gene Chr9:24388680-24417223 (-)
PWK/PhJ MGP_PWKPhJ_G0033214
 protein coding gene Chr9:23856852-23882674 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033048
 protein coding gene Chr9:24442041-24471593 (-)
WSB/EiJ MGP_WSBEiJ_G0033624
 protein coding gene Chr9:24113125-24138577 (-)



Homology
more
  • Human Ortholog
    VPS26B, VPS26 retromer complex component B
  • Vertebrate Orthologs
    4
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    VPS26B, VPS26 retromer complex component B
  • Synonyms
    Pep8b
  • Links
    NCBI Gene ID: 112936
    neXtProt AC: NX_Q4G0F5
    UniProt: Q4G0F5

  • Chr Location
    11q25; chr11:134224671-134247788 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    8 phenotype references
Mice homozygous for a knock-out allele exhibit normal behavior, growth, and health.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    771
  • Tissues
    54
  • cDNA Data
    22
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000031988 Ensembl Gene Model | MGI Sequence Detail 22295 C57BL/6J ±  kb
transcript ENSMUST00000034470 Ensembl | MGI Sequence Detail 3575 Not Applicable  
polypeptide ENSMUSP00000034470 Ensembl | MGI Sequence Detail 336 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 22
    cDNA 22

    Microarray probesets 6
Other
Accession IDs
less
MGI:1916341, MGI:2143146
References
more
  • Summaries
    All 35
    Developmental Gene Expression 3
    Gene Ontology 7
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:328738 Simoes S, et al., Alzheimer's vulnerable brain region relies on a distinct retromer core dedicated to endosomal recycling. Cell Rep. 2021 Dec 28;37(13):110182
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory