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Ankrd26 Gene Detail
Summary
  • Symbol
    Ankrd26
  • Name
    ankyrin repeat domain 26
  • Synonyms
    5730521P14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1917887
    NCBI Gene: 232339
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr6:118478269-118539187 bp, - strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 6, 55.86 cM, cytoband F1
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    2169 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1917887
 protein coding gene Chr6:118478261-118539244 (-)
129S1/SvImJ MGP_129S1SvImJ_G0031188
 protein coding gene Chr6:121248861-121314140 (-)
A/J MGP_AJ_G0031157
 protein coding gene Chr6:116616115-116677456 (-)
AKR/J MGP_AKRJ_G0031088
 protein coding gene Chr6:119738879-119801421 (-)
BALB/cJ MGP_BALBcJ_G0031168
 protein coding gene Chr6:116387873-116449144 (-)
C3H/HeJ MGP_C3HHeJ_G0030541
 protein coding gene Chr6:64492881-64553527 (+)
C57BL/6NJ MGP_C57BL6NJ_G0031626
 protein coding gene Chr6:124374631-124444454 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0028787
 protein coding gene Chr6:113587815-113593187 (-)
CAST/EiJ MGP_CASTEiJ_G0030275
 protein coding gene Chr6:120148673-120216835 (-)
CBA/J MGP_CBAJ_G0030851
 protein coding gene Chr6:129285127-129351265 (-)
DBA/2J MGP_DBA2J_G0031007
 protein coding gene Chr6:115505758-115568073 (-)
FVB/NJ MGP_FVBNJ_G0030959
 protein coding gene Chr6:114637589-114700902 (-)
LP/J MGP_LPJ_G0031086
 protein coding gene Chr6:121278088-121342898 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0030993
 protein coding gene Chr6:133361220-133427734 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0031655
 protein coding gene Chr6:119773291-119835046 (-)
PWK/PhJ MGP_PWKPhJ_G0029990
 protein coding gene Chr6:114523331-114586338 (-)
SPRET/EiJ MGP_SPRETEiJ_G0029819
 protein coding gene Chr6:118489884-118554118 (-)
WSB/EiJ MGP_WSBEiJ_G0030358
 protein coding gene Chr6:120041912-120104602 (-)



Homology
more
  • Human Ortholog
    ANKRD26, ankyrin repeat domain containing 26
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ANKRD26, ankyrin repeat domain containing 26
  • Synonyms
    bA145E8.1, THC2
  • Links
    NCBI Gene ID: 22852
    neXtProt AC: NX_Q9UPS8
    UniProt: Q9UPS8

  • Chr Location
    10p12.1; chr10:26947582-27100494 (-)  GRCh38
Human Diseases
more
  • Diseases
    1 with Ankrd26 mouse models; 1 with human ANKRD26 associations

Human Disease Mouse Models
      
IDs
 View 1 model
      
IDs
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    16 phenotypes from 1 allele in 1 genetic background
    2 images
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a gene trapped allele have enlarged kidneys and hearts, exhibit increased lean body mass and adiposity, develop extreme obesity associated with hyperphagia rather than reduced energy expenditure, and show insulin resistance and gigantism.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    18
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    727
  • Tissues
    16
  • cDNA Data
    52
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000007827 Ensembl Gene Model | MGI Sequence Detail 60919 C57BL/6J ±  kb
    transcript ENSMUST00000112830 Ensembl | MGI Sequence Detail 6930 Not Applicable  
    polypeptide ENSMUSP00000108449 Ensembl | MGI Sequence Detail 1681 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 54
      cDNA 52
      Primer pair 1
      Other 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2448538
    References
    more
    • Summaries
      All 36
      Developmental Gene Expression 1
      Diseases 1
      Gene Ontology 7
      Phenotypes 11
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:332592 Sladky VC, et al., Centriole signaling restricts hepatocyte ploidy to maintain liver integrity. Genes Dev. 2022 Aug 18;36(13-14):843-56
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory