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Dennd1c Gene Detail
Summary
  • Symbol
    Dennd1c
  • Name
    DENN domain containing 1C
  • Synonyms
    4432409M07Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918035
    NCBI Gene: 70785
  • Alliance
    genome feature page
  • Transcription Start Sites
    7 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:57373051-57385518 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 17, 29.65 cM, cytoband E1.1
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    388 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918035
 protein coding gene Chr17:57372905-57385518 (-)
129S1/SvImJ ENSMUSG00200015736
 protein coding gene Chr17:52648659-52661285 (-)
A/J ENSMUSG00195006691
 protein coding gene Chr17:54036469-54048928 (-)
AKR/J ENSMUSG00220012339
 protein coding gene Chr17:53085817-53098280 (-)
BALB/cJ ENSMUSG00180006174
 protein coding gene Chr17:53794130-53806592 (-)
C3H/HeJ ENSMUSG00175006928
 protein coding gene Chr17:53110102-53122561 (-)
C57BL/6NJ ENSMUSG00215005842
 protein coding gene Chr17:52724280-52736737 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021804
 protein coding gene Chr17:53669119-53681370 (-)
CAST/EiJ ENSTCUG00005018323
 protein coding gene Chr17:53841892-53854360 (-)
CBA/J ENSMUSG00210028654
 protein coding gene Chr17:52877147-52889615 (-)
DBA/2J ENSMUSG00185008234
 protein coding gene Chr17:55747002-55759461 (-)
FVB/NJ ENSMUSG00205006477
 protein coding gene Chr17:53424501-53436979 (-)
JF1/MsJ ENSUMUG00000015025
 protein coding gene Chr17:55434633-55446067 (-)
LP/J ENSMUSG00230028333
 protein coding gene Chr17:56726145-56738627 (-)
NOD/ShiLtJ ENSMUSG00190010018
 protein coding gene Chr17:52879708-52892185 (-)
NZO/HlLtJ ENSMUSG00225043052
 protein coding gene Chr17:59010025-59022633 (-)
PWK/PhJ ENSLUMG00010008584
 protein coding gene Chr17:52686117-52698803 (-)
SPRET/EiJ no annotation
WSB/EiJ ENSIUOG00005021666
 protein coding gene Chr17:53785493-53797966 (-)



Homology
more
  • Human Ortholog
    DENND1C, DENN domain containing 1C
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DENND1C, DENN domain containing 1C
  • Synonyms
    FAM31C
  • Links
    NCBI Gene ID: 79958
    UniProt: Q8IV53

  • Chr Location
    19p13.3; chr19:6467207-6482557 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    16
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    597
  • cDNA Data
    26
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 70785 NCBI Gene Model | MGI Sequence Detail 12468 C57BL/6J ±  kb
transcript NM_153551 RefSeq | MGI Sequence Detail 2509 C57BL/6  
polypeptide Q8CFK6 UniProt | EBI | MGI Sequence Detail 786 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    cDNA 26

    Microarray probesets 3
References
more
  • Summaries
    All 36
    Gene Ontology 7
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory