Slco6d1 MGI Mouse Gene Detail - MGI:1918116 - solute carrier organic anion transporter family, member 6d1

Symbol

Slco6d1
Name

solute carrier organic anion transporter family, member 6d1
Synonyms

4921511I05Rik

Feature Type

protein coding gene
IDs

MGI:1918116
NCBI Gene: 70866
Alliance

gene page
Transcription Start Sites

1 TSS

Sequence Map

Chr1:98348849-98444716 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 1, 47.76 cM, cytoband D
Mapping Data

2 experiments

SNPs within 2kb

3014 from dbSNP Build 142
Strain Annotations

17

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1918116	protein coding gene	Chr1:98348812-98444716 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0016362	protein coding gene	Chr1:100191235-100299623 (+)
A/J	MGP_AJ_G0016346	protein coding gene	Chr1:96676161-96776735 (+)
AKR/J	MGP_AKRJ_G0016306	protein coding gene	Chr1:99495563-99593615 (+)
BALB/cJ	MGP_BALBcJ_G0016302	protein coding gene	Chr1:96834827-96947265 (+)
C3H/HeJ	MGP_C3HHeJ_G0016129	protein coding gene	Chr1:99775204-99880179 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0016761	protein coding gene	Chr1:104169031-104269069 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0014479	protein coding gene	Chr1:90918670-91096852 (+)
CAST/EiJ	MGP_CASTEiJ_G0015711	protein coding gene	Chr1:98882611-98974873 (+)
CBA/J	MGP_CBAJ_G0016102	protein coding gene	Chr1:107575888-107689312 (+)
DBA/2J	MGP_DBA2J_G0016207	protein coding gene	Chr1:95896758-96009313 (+)
FVB/NJ	MGP_FVBNJ_G0016208	protein coding gene	Chr1:94887151-94989749 (+)
LP/J	MGP_LPJ_G0016281	protein coding gene	Chr1:101484410-101586191 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0016234	protein coding gene	Chr1:111282575-111401180 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0016800	protein coding gene	Chr1:99531373-99626520 (+)
PWK/PhJ	no annotation
SPRET/EiJ	MGP_SPRETEiJ_G0015283	protein coding gene	Chr1:98353080-98456220 (+)
WSB/EiJ	MGP_WSBEiJ_G0015774	protein coding gene	Chr1:99332638-99453744 (+)

Human Ortholog

SLCO6A1, solute carrier organic anion transporter family member 6A1

Vertebrate Orthologs

2

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

SLCO6A1, solute carrier organic anion transporter family member 6A1
Synonyms

CT48, GST, OATP6A1, OATP-I, OATPY
Links

HGNC:23613

NCBI Gene ID: 133482

neXtProt AC: NX_Q86UG4

UniProt: Q86UG4
Chr Location

5q21.1; chr5:102371774-102499016 (-) GRCh38

MGI Vertebrate Homology

Slco6d1 stringent orthology
1 human;1 mouse;1 rat
HCOP

vertebrate homology predictions: SLCO6A1
Gene Tree

Slco6d1

less

Phenotype Summary

1 phenotype from 1 allele in 1 genetic background
11 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

6
Chemically induced (other)

1
Endonuclease-mediated

2
Gene trapped

1
Radiation induced

1
Targeted

1
Genomic Mutations

2 involving Slco6d1
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

48 strains or lines available
Comparison Matrix

Gene Expression + Phenotype

less

All GO Annotations

3
GO References

1

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

less

Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

5

Tissue x Stage Matrix

Comparison Matrix

Gene Expression + Phenotype

Other Mouse Links

Allen Institute

GEO

Expression Atlas

less

All Sequences

52
RefSeq

18
UniProt

3
CCDS

CCDS48332.1, CCDS48333.1

Ensembl

ENSMUSG00000026336 (Evidence)
NCBI Gene

70866

			Length	Strain/Species	Flank
genomic	ENSMUSG00000026336	Ensembl Gene Model \| MGI Sequence Detail	95868	C57BL/6J	± kb
transcript	ENSMUST00000027575	Ensembl \| MGI Sequence Detail	2328	Not Applicable
polypeptide	ENSMUSP00000027575	Ensembl \| MGI Sequence Detail	683	Not Applicable

less

UniProt

3 Sequences
InterPro Domains

IPR002350 Kazal domain

IPR036058 Kazal domain superfamily

IPR036259 MFS transporter superfamily

IPR004156 Organic anion transporter polypeptide

less

All nucleic 5

cDNA 5

Microarray probesets 2

Summaries

All 27

Gene Ontology 1

Phenotypes 11
Earliest

J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
Latest

J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136

TSS for Slco6d1:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr8236	Chr1:98348817-98348859 (+)	-11 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/12/2024 MGI 6.24