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Dap Gene Detail
Summary
  • Symbol
    Dap
  • Name
    death-associated protein
  • Synonyms
    4921531N22Rik, MGC:19154, MGC:6998
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918190
    NCBI Gene: 223453
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:31224531-31274484 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 12.67 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1808 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918190
 protein coding gene Chr15:31224460-31274487 (+)
129S1/SvImJ MGP_129S1SvImJ_G0021762
 protein coding gene Chr15:29427725-29480222 (+)
A/J MGP_AJ_G0021722
 protein coding gene Chr15:28266442-28317018 (+)
AKR/J MGP_AKRJ_G0021700
 protein coding gene Chr15:28992128-29041937 (+)
BALB/cJ MGP_BALBcJ_G0021729
 protein coding gene Chr15:28266273-28316628 (+)
C3H/HeJ MGP_C3HHeJ_G0021504
 protein coding gene Chr15:29003116-29053844 (+)
C57BL/6NJ MGP_C57BL6NJ_G0022168
 protein coding gene Chr15:30626763-30682998 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0019707
 protein coding gene Chr15:26368800-26418357 (+)
CAST/EiJ MGP_CASTEiJ_G0021020
 protein coding gene Chr15:29501427-29549476 (+)
CBA/J MGP_CBAJ_G0021473
 protein coding gene Chr15:31509165-31561139 (+)
DBA/2J MGP_DBA2J_G0021597
 protein coding gene Chr15:28074759-28127564 (+)
FVB/NJ MGP_FVBNJ_G0021575
 protein coding gene Chr15:27595355-27644903 (+)
LP/J MGP_LPJ_G0021666
 protein coding gene Chr15:29313247-29364541 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0021600
 protein coding gene Chr15:34483425-34534250 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0022191
 protein coding gene Chr15:29225977-29278802 (+)
PWK/PhJ MGP_PWKPhJ_G0020764
 protein coding gene Chr15:28231480-28281565 (+)
SPRET/EiJ MGP_SPRETEiJ_G0020602
 protein coding gene Chr15:29021650-29071360 (+)
WSB/EiJ MGP_WSBEiJ_G0021076
 protein coding gene Chr15:29184251-29234910 (+)



Homology
more
  • Human Ortholog
    DAP, death associated protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    DAP, death associated protein
  • Synonyms
    DAP1
  • Links
    NCBI Gene ID: 1611
    neXtProt AC: NX_P51397
    UniProt: P51397

  • Chr Location
    5p15.2; chr5:10679230-10761234 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotypes from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

No experimental evidence to support Cellular Component annotation, following literature review. See J:73796.
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    800
  • Tissues
    11
  • cDNA Data
    213
  • Literature Summary
    3
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 223453 NCBI Gene Model | MGI Sequence Detail 49954 C57BL/6J ±  kb
    transcript NM_146057 RefSeq | MGI Sequence Detail 1481 C57BL/6  
    polypeptide Q91XC8 UniProt | EBI | MGI Sequence Detail 102 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 214
      cDNA 213
      Primer pair 1

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2146061, MGI:2146148
    References
    more
    • Summaries
      All 43
      Developmental Gene Expression 3
      Gene Ontology 5
      Phenotypes 12
    • Earliest
      J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/12/2024
    MGI 6.24     		The Jackson Laboratory