Uvssa MGI Mouse Gene Detail - MGI:1918351 - UV stimulated scaffold protein A

Symbol

Uvssa
Name

UV stimulated scaffold protein A
Synonyms

4933407H18Rik, D330017J19Rik, mKIAA1530

Feature Type

protein coding gene
IDs

MGI:1918351
NCBI Gene: 71101
Alliance

gene page
Transcription Start Sites

3 TSS

Sequence Map

Chr5:33535893-33577098 bp, + strand
From Ensembl annotation of GRCm39
View this region in JBrowse
Genome Browsers

Ensembl | UCSC | NCBI

Genetic Map

Chromosome 5, 17.60 cM, cytoband B1
Mapping Data

2 experiments

SNPs within 2kb

794 from dbSNP Build 142
Strain Annotations

18

For selected strains:

Strain	Gene Model ID	Feature Type	Coordinates
C57BL/6J	MGI_C57BL6J_1918351	protein coding gene	Chr5:33535868-33578243 (+)
129S1/SvImJ	MGP_129S1SvImJ_G0029445	protein coding gene	Chr5:31550648-31593914 (+)
A/J	MGP_AJ_G0029412	protein coding gene	Chr5:30523616-30565363 (+)
AKR/J	MGP_AKRJ_G0029361	protein coding gene	Chr5:31701246-31743666 (+)
BALB/cJ	MGP_BALBcJ_G0029422	protein coding gene	Chr5:31053112-31095369 (+)
C3H/HeJ	MGP_C3HHeJ_G0029144	protein coding gene	Chr5:31739508-31785739 (+)
C57BL/6NJ	MGP_C57BL6NJ_G0029876	protein coding gene	Chr5:33435083-33477235 (+)
CAROLI/EiJ	MGP_CAROLIEiJ_G0027113	protein coding gene	Chr5:28320721-28362879 (+)
CAST/EiJ	MGP_CASTEiJ_G0028553	protein coding gene	Chr5:30820576-30865215 (+)
CBA/J	MGP_CBAJ_G0029112	protein coding gene	Chr5:34134932-34176789 (+)
DBA/2J	MGP_DBA2J_G0029260	protein coding gene	Chr5:30703312-30744512 (+)
FVB/NJ	MGP_FVBNJ_G0029219	protein coding gene	Chr5:30125952-30166977 (+)
LP/J	MGP_LPJ_G0029345	protein coding gene	Chr5:31967105-32008657 (+)
NOD/ShiLtJ	MGP_NODShiLtJ_G0029249	protein coding gene	Chr5:34993587-35045167 (+)
NZO/HlLtJ	MGP_NZOHlLtJ_G0029909	protein coding gene	Chr5:31218024-31259184 (+)
PWK/PhJ	MGP_PWKPhJ_G0028278	protein coding gene	Chr5:29827302-29869401 (+)
SPRET/EiJ	MGP_SPRETEiJ_G0028109	protein coding gene	Chr5:30668093-30711677 (+)
WSB/EiJ	MGP_WSBEiJ_G0028634	protein coding gene	Chr5:31274818-31319324 (+)

Human Ortholog

UVSSA, UV stimulated scaffold protein A

Vertebrate Orthologs

3

Vertebrate Orthology Source

Alliance of Genome Resources

Human Ortholog

UVSSA, UV stimulated scaffold protein A
Synonyms

KIAA1530, UVSS3
Links

HGNC:29304

NCBI Gene ID: 57654

neXtProt AC: NX_Q2YD98

UniProt: Q2YD98
Chr Location

4p16.3; chr4:1342011-1395989 (+) GRCh38

MGI Vertebrate Homology

Uvssa stringent orthology
1 human;1 mouse;1 rat;1 zebrafish
HCOP

vertebrate homology predictions: UVSSA
Gene Tree

Uvssa

Diseases

1 with human UVSSA associations

				Human Disease	Mouse Models
				UV-sensitive syndrome IDs UV-sensitive syndrome DOID:0060240 MESH:C563466 OMIM:600630 OMIM:614621 OMIM:614640 OMIM:PS600630 ORDO:178338

Click on a disease name to see all genes associated with that disease.

References

1 with disease annotations

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Phenotype Summary

25 phenotype references

All Mutations and Alleles

14
Chemically induced (ENU)

1
Chemically induced (other)

2
Endonuclease-mediated

1
Gene trapped

3
Radiation induced

3
Spontaneous

1
Targeted

3
Genomic Mutations

7 involving Uvssa
Incidental Mutations

APF , CvDC
Find Mice (IMSR)

38 strains or lines available

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All GO Annotations

16
GO References

4

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	RNA binding	signaling receptor activity	signaling receptor binding	transcription	transferase	transporter

Biological Process

carbohydrate derivative metabolism	cell differentiation	cell population proliferation	cellular component organization	DNA-templated transcription	establishment of localization	homeostatic process	immune system process	lipid metabolic process	programmed cell death	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	membraneless organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	protein-containing complex	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

706
cDNA Data

37

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas
Other Vertebrate Links

Xenbase uvssa

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All Sequences

59
RefSeq

13
UniProt

2
CCDS

CCDS39064.1

Ensembl

ENSMUSG00000037355 (Evidence)
NCBI Gene

71101

			Length	Strain/Species	Flank
genomic	ENSMUSG00000037355	Ensembl Gene Model \| MGI Sequence Detail	41206	C57BL/6J	± kb
transcript	ENSMUST00000087864	Ensembl \| MGI Sequence Detail	7326	Not Applicable
polypeptide	ENSMUSP00000085170	Ensembl \| MGI Sequence Detail	717	Not Applicable

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UniProt

2 Sequences
Protein Ontology

PR:000031447 UV-stimulated scaffold protein A

(term hierarchy)
InterPro Domains

IPR008942 ENTH/VHS

IPR018610 UV-stimulated scaffold protein A

IPR049431 UV-stimulated scaffold protein A, C-terminal domain

IPR049408 UV-stimulated scaffold protein A, N-terminal alpha-solenoid repeats

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All nucleic 38

cDNA 38

Microarray probesets 4

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MGI:2443980

Summaries

All 51

Diseases 1

Gene Ontology 4

Phenotypes 25
Earliest

J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
Latest

J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

TSS for Uvssa:

(View these features in JBrowse)

Transcription Start Site	Location	Distance from Gene 5'-end
Tssr45820	Chr5:33535873-33535928 (+)	8 bp
Tssr45821	Chr5:33536073-33536142 (+)	215 bp
Tssr45822	Chr5:33575198-33575202 (+)	39,307 bp

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24